Clinical Assessment and Management in Improving the Quality of Life of HIV/AIDS Patients with Oral Candidiasis: A Case Series

IF 1.5 Q4 INFECTIOUS DISEASES
Yessy Novianti, Irna Sufiawati
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Abstract

Introduction: Oral candidiasis is the most prevalent opportunistic infection in patients with human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS), impacting their quality of life. This report aims to emphasize the importance of clinical assessment and management of HIV/AIDS patients with oral candidiasis to improve their quality of life. Case: Five male patients, aged between 32 and 71 years, came to the HIV clinic and complained of white plaques in their mouths and painful swallowing. The World Health Organization’s (WHO) clinical staging of all patients was 4. Three patients had not yet received antiretroviral therapy (ART), and their total lymphocyte counts (TLC) of < 1.170 cells/mm 3 . Two patients had dropped out of ART with CD4 counts were < 40 cells/mm 3 . The body mass index of two patients was underweight, while the others were normal. The oral hygiene index simplified (OHI-S) of the patients was fair to poor. The quality of life assessment using the oral health impact profile 14 (OHIP-14) questionnaires before therapy showed values from 6– 20. Clinical examination defined the diagnosis as oral candidiasis, exfoliative cheilitis, oral hairy leukoplakia, and a cytomegalovirus-related ulcer. Case Management: The patients were treated with fluconazole, 0.2% chlorhexidine gluconate mouthwash, 2% miconazole cream, diphenhydramine, and multivitamins. The oral lesions were improved within 14 days to a month of treatment, and OHIP-14 scores were significantly reduced (0– 3). Conclusion: Clinical assessment is important in managing HIV/AIDS patients with oral candidiasis, which improves the patient’s quality of life. Therefore, routine clinical assessment and management of HIV/AIDS patients are strongly recommended. Keywords: AIDS, HIV, oral candidiasis, quality of life
改善HIV/AIDS口腔念珠菌病患者生活质量的临床评估与管理:一个病例系列
口腔念珠菌病是人类免疫缺陷病毒(HIV)或获得性免疫缺陷综合征(AIDS)患者中最常见的机会性感染,影响其生活质量。本报告旨在强调临床评估和管理HIV/AIDS口腔念珠菌病患者对改善其生活质量的重要性。病例:5例男性患者,年龄32 ~ 71岁,来HIV门诊就诊,自诉口腔白斑,吞咽疼痛。世界卫生组织(WHO)对所有患者的临床分期为4。3例患者未接受抗逆转录病毒治疗(ART),总淋巴细胞计数(TLC) < 1.170细胞/mm 3。2例患者因CD4细胞计数< 40细胞/mm 3而退出抗逆转录病毒治疗。其中2例体重指数过轻,其余均正常。患者的口腔卫生简化指数(OHI-S)为中差。治疗前使用口腔健康影响量表14 (OHIP-14)进行生活质量评估的数值为6 - 20。临床检查诊断为口腔念珠菌病、剥脱性口唇炎、口腔毛状白斑和巨细胞病毒相关溃疡。病例处理:患者给予氟康唑、0.2%葡萄糖酸氯己定漱口水、2%咪康唑乳膏、苯海拉明和多种维生素治疗。治疗14天至1个月,口腔病变得到改善,o嘻哈-14评分明显降低(0 - 3)。结论:临床评估对管理HIV/AIDS合并口腔念珠菌病患者具有重要意义,可提高患者的生活质量。因此,强烈建议对HIV/AIDS患者进行常规的临床评估和管理。关键词:艾滋病,HIV,口腔念珠菌病,生活质量
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来源期刊
CiteScore
3.00
自引率
6.70%
发文量
61
审稿时长
16 weeks
期刊介绍: About Dove Medical Press Dove Medical Press Ltd is part of Taylor & Francis Group, the Academic Publishing Division of Informa PLC. We specialize in the publication of Open Access peer-reviewed journals across the broad spectrum of science, technology and especially medicine. Dove Medical Press was founded in 2003 with the objective of combining the highest editorial standards with the ''best of breed'' new publishing technologies. We have offices in Manchester and London in the United Kingdom, representatives in Princeton, New Jersey in the United States, and our editorial offices are in Auckland, New Zealand. Dr Scott Fraser is our Medical Director based in the UK. He has been in full time clinical practice for over 20 years as well as having an active research interest.
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