Malignant struma ovarii- Report of a rare case

Chhaya Shevra, Himanshu Kumar
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Abstract

Struma ovarii is a highly specialized form of mature ovarian teratoma in which the ovary contains >50% of thyroid tissue. It accounts for 1 – 3% of benign teratomas of the ovary. Malignant transformation is observed in 5-37% cases of struma ovarii. Peak age of incidence 4 - 5th decade with excellent prognosis. We report a rare form of malignant struma ovarii, composed of a follicular variant of papillary thyroid carcinoma with capsular invasion. A65-year-old hypertensive postmenopausal female presented with complaints of pain in abdomen, pelvic mass, frequent micturition, since 3 days. A pelvic sonogram showed an enlarged heterogenous right ovarian mass of sized 12 x 9 x 5 cm, with solid cystic lesion. Left ovary was unilocular and cystic of sized 5.5 x 4 x 3 cm. The uterus and cervix appeared to be normal. She underwent an exploratory laparotomy, and a total abdominal hysterectomy with bilateral salpingo-oophorectomy. Based on histopathological and radiological features an impression of follicular variant of papillary carcinoma of thyroid with capsular invasion was favoured. : The patient was successfully treated with total abdominal hysterectomy with bilateral salpingo-oopherectomy. There are no sign of recurrence and metastasis two months after surgery. Patient is under regular follow up. : Malignant struma ovarii is a medical rarity and very few studies have been reported.
卵巢恶性肿瘤1例报告
卵巢甲状腺肿是一种高度特化的成熟卵巢畸胎瘤,其中卵巢含有50%的甲状腺组织。它占卵巢良性畸胎瘤的1 - 3%。卵巢瘤中有5-37%发生恶性转化。发病高峰年龄为4 - 5岁,预后良好。我们报告一个罕见的恶性卵巢瘤,由滤泡变异的甲状腺乳头状癌与包膜侵袭组成。65岁绝经后高血压女性,主诉腹痛、盆腔肿块、尿频3天。盆腔超声示右侧卵巢肿物,大小为12 × 9 × 5 cm,伴实性囊性病变。左卵巢单眼,囊性,大小5.5 x 4 x 3 cm。子宫和子宫颈看起来正常。她接受了探查性剖腹手术,并进行了全腹子宫切除术和双侧输卵管卵巢切除术。根据组织病理学和放射学特征,甲状腺乳头状癌的滤泡变异型伴包膜侵袭的印象是有利的。患者成功行全腹子宫双侧输卵管卵巢切除术。术后2个月无复发和转移迹象。病人正在接受定期随访。卵巢恶性肿瘤在医学上是罕见的,很少有研究报道。
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