Predictors of Prediabetes and Undiagnosed Diabetes Mellitus Based on HbA1c Levels in Indonesia

Irma Surya Kusuma, Syahrizal Syarif
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Abstract

Prediabetes and Undiagnosed Diabetes Mellitus (UDDM) are associated with an increased risk of diabetes complications and other cardiovascular diseases. Early detection of both health problems is expected to reduce the burden of non-communicable diseases in the future. The purpose of this study is to investigate predictors of prediabetes and UDDM based on HbA1c levels among population ≥ 15 years old in Indonesia. This cross-sectional study involved 6,065 respondents of Indonesian Family Life Survey 5 (IFLS 5) who met the inclusion and exclusion criteria. Data associated with sociodemographic characteristics, lifestyle risk factors, hypertension, and obesity were obtained. Prediabetes was defined as HbA1c between 5.7-6.4%, while diabetes was defined as HbA1c ≥ 6.5%. Multinomial logistic regression analysis was performed to estimate adjusted Odds Ratio (aOR). The results showed that predictors of prediabetes were age, gender, marital status, and obesity, while predictors of UDDM were age, hypertension, and obesity. Identification of risk factors and early detection of prediabetes and UDDM is important, so that appropriate intervention can be given immediately to prevent complications.
印度尼西亚基于HbA1c水平的前驱糖尿病和未确诊糖尿病的预测因子
糖尿病前期和未确诊糖尿病(UDDM)与糖尿病并发症和其他心血管疾病的风险增加有关。早期发现这两种健康问题预计将在未来减轻非传染性疾病的负担。本研究的目的是研究印度尼西亚≥15岁人群中基于HbA1c水平的前驱糖尿病和UDDM的预测因素。本横断面研究涉及6,065名符合纳入和排除标准的印度尼西亚家庭生活调查5 (IFLS 5)受访者。获得了与社会人口学特征、生活方式危险因素、高血压和肥胖相关的数据。糖尿病前期定义为HbA1c在5.7-6.4%之间,糖尿病定义为HbA1c≥6.5%。采用多项logistic回归分析估计调整优势比(aOR)。结果显示,糖尿病前期的预测因子为年龄、性别、婚姻状况和肥胖,而UDDM的预测因子为年龄、高血压和肥胖。确定危险因素和早期发现糖尿病前期和UDDM是很重要的,因此可以立即采取适当的干预措施以预防并发症。
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