New-onset severe Diabetic Ketoacidosis in a 13-months old Nepali Toddler: a case report

Bijay Basnet, Chaitanya Darshan Bhattarai, Rohit Bhatt, Romila Chimoriya, Kushal Adhikari, Birendra Kumar Yadav
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Abstract

Diabetes mellitus (DM) is a glucose metabolism disorder with diabetic ketoacidosis (DKA) being the most common complication associated with significant morbidity and mortality. Unlike other patients with typical symptoms of abdominal discomfort, pain, nausea and emesis of DKA, our patient presented with atypical symptoms such as cough, runny nose and fast breathing. This symptoms would have initially misled with diagnosis of respiratory tract infection, which would have caused delay in the treatment of DKA. In our patient DKA was treated with intravenous fluid replacement followed by intravenous insulin infusion, along with monitoring of blood glucose and electrolyte levels. We would like to emphasize that DKA can be precipitated by simple upper respiratory tract infection in toddlers with undiagnosed type 1 DM. Hence, random blood sugar measurement and urine for ketone bodies test should be performed if feasible in sick patients presenting with respiratory tract illness-like symptoms.
13个月尼泊尔幼童新发严重糖尿病酮症酸中毒1例报告
糖尿病(DM)是一种糖代谢紊乱,糖尿病酮症酸中毒(DKA)是最常见的并发症,具有显著的发病率和死亡率。与其他DKA患者腹部不适、疼痛、恶心、呕吐等典型症状不同,我们的患者表现为咳嗽、流鼻涕、呼吸急促等非典型症状。这种症状最初可能会误导呼吸道感染的诊断,从而导致DKA治疗的延误。在我们的患者中,DKA的治疗是静脉补液,然后静脉注射胰岛素,同时监测血糖和电解质水平。我们想强调的是,在未确诊的1型糖尿病幼儿中,单纯性上呼吸道感染可诱发DKA。因此,对于出现呼吸道疾病样症状的患者,在可行的情况下应随机进行血糖和尿酮体检测。
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