Formulation Options for Mucoadhesive Dosage Forms for Use in the Oral Cavity

European Pharmaceutical Journal Pub Date : 2023-09-13 DOI:10.2478/afpuc-2023-0012

V. Šimunková, E. Tichý, M. Špaglová, M. Potúčková

引用次数: 0

Abstract

Abstract Mucoadhesive dosage forms, which are used for topical application in the oral cavity, are currently a very intensively developing field in pharmaceutical technology. Considering the physiological conditions of the oral cavity, the formulation of these mucoadhesive forms is still a challenge. Various types and forms of polymers are used in the experiments, in combination with a large number of drugs, while the achieved effect can be local or systemic and the release rate can be controlled. For many drugs, buccal application is one of the ways to increase their bioavailability.

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口腔用黏液胶剂型的配方选择

摘要黏附剂型用于口腔外用，是目前制药技术中发展非常迅速的一个领域。考虑到口腔的生理条件，这些黏附形式的配方仍然是一个挑战。实验中使用了各种类型和形式的聚合物，与大量药物联合使用，所达到的效果可以是局部的，也可以是全身的，并且释放速度是可以控制的。对于许多药物，口腔应用是提高其生物利用度的方法之一。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Pharmaceutical Journal Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)

CiteScore

0.60

自引率

0.00%

发文量

期刊介绍： European Pharmaceutical Journal publishes only original articles not previously published and articles that are not being considered or have not been submitted for publication elsewhere. If parts of the results have been published as conference abstract or elsewhere, it should be stated in references. The ethical standards of the Helsinki-Tokio Declaration should be kept. This should be mentioned in the Methods of manuscript. Reviews are published only on request. Authors, whose submitted research work was performed with the support of a company, should indicate this in Conflict of Interest.