Pemphigus Herpetiformis in Childhood: Clinical Case

Q4 Medicine

Voprosy Sovremennoi Pediatrii - Current Pediatrics Pub Date : 2023-11-06 DOI:10.15690/vsp.v22i5.2636

Nikolay N. Murashkin, Alexander I. Materikin, Roman V. Epishev, Maria A. Leonova, Leonid A. Opryatin, Dmitri V. Fedorov, Roman A. Ivanov, Alena A. Savelova, Oksana R. Katunina, Kirill A. Kulikov, Ilgiz I. Yarullin

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引用次数: 0

Abstract

Background. Pemphigus herpetiformis is a rare atypical bullous dermatosis of autoimmune nature. It is characterized by rashes in the form of plaques with papules and vesicles at peripheral areas, or in the form of grouped papules, vesicles or tense bubbles with clinical similarity to During's herpetiformis dermatitis. Pemphigus herpetiformis diagnosis in pediatric practice is difficult due to the similarity of clinical manifestations to bullous dermatoses of other etiology, the rarity of the disease in children, and small number of scientific publications. Clinical case description . Clinical case of pemphigus herpetiformis in a child is described. All necessary diagnostic algorithms for diagnosis and therapeutic tactics for patient management are presented. Dapsone and prednisolone were used as first-line drugs during the patient's treatment. They have shown its efficacy in management of such patients. Conclusion . Differential diagnosis of pemphigus herpetiformis and other bullous dermatoses in children is presented. The results of successful drug treatment are shown.

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儿童期疱疹样天疱疮临床一例

背景。疱疹样天疱疮是一种罕见的自身免疫性大疱性皮肤病。它的特点是在周围区域出现斑块、丘疹和小泡，或以成组丘疹、小泡或紧张气泡的形式出现，临床与During的疱疹样皮炎相似。由于临床表现与其他病因的大疱性皮肤病相似，儿童罕见，科学出版物少，因此在儿科实践中诊断疱疹样天疱疮是困难的。临床病例描述。描述了一个儿童疱疹样天疱疮的临床病例。提出了所有必要的诊断算法和患者管理的治疗策略。在患者治疗期间，应用氨苯砜和强的松龙作为一线药物。他们已经证明了它在治疗这类病人方面的有效性。结论。提出了儿童疱疹样天疱疮和其他大疱性皮肤病的鉴别诊断。显示了药物治疗成功的结果。

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来源期刊

Voprosy Sovremennoi Pediatrii - Current Pediatrics Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.70

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： The main purpose of the academic journal "Current Pediatrics" is to cover the issues related to health, emotional state, and social adaptation of children. In the journal we publish the most pressing issues of research and applied problems (such as social paediatrics; clinical findings, anamnesis, and diagnosis of paediatric diseases; prevention and rehabilitation; supply of healthy and sick child), reviews on the current state of medical science and management of health care in Russia. Along with the concern for providing a high level of basic research publications, the journal, being a mass media tool, tends to meet the interests and requirements of practitioners from different regions and bring up vital and urgent questions. To accomplish this purpose the journal includes the materials of practical interest presented in the following sections: "Exchange of experience", "Doctor''s aid", "Continuous professional education", "Expert Opinion". The journal presents actual official information from the Union of Paediatricians of Russia and publishes materials on the history of medical science, congresses, seminars, conferences, both in our country and abroad.