Evaluation of Biochemical Parameters of Patients with Type 2 Diabetes Mellitus Based on Age and Gender in Umuahia

Abstract

Diabetes mellitus is a major public health issue. The study was done to determine the changes in some biochemical parameters between type 2 diabetes mellitus patients and apparently healthy adults in Umuahia. The fasting blood glucose was significantly higher in females than in males in the diabetic population. The table revealed a significantly (P<0.05) higher levels of serum total cholesterol, trialytglycerol, LDL-cholesterol, in females than males, except low HDL cholesterol (P<0.05) compared to male matched patients. Glycated haemoglobin was significantly (P<0.05) higher in female than male. Creatinine was significantly (P<0.05) higher in male. Urea was also significantly (P<0.05) higher in female. Potassium was significantly (P<0.05) higher in females. Bicarbonate was significantly (P<0.05) lower in female.The study showed a significantly (P<0.05) higher levels of total cholesterol, trialyglycerol, LDL- cholesterol in patient’s aged between 57-74years, except low HDL-cholesterol (P<0.05) compared to those aged between 40-56years. Fasting blood glucose and HbAIC were significantly (P<0.05) higher in age limit 57-74years than 40-56years. Urea and creatinine were significantly (P<0.05) low in patients aged 57-74years when compared to age 40-56years. However, HDL concentration was significantly (P<0.05) high in the 40-56years when compared to 57-74years.Elevated levels of triglyceride (TG), total cholesterol (TC), and glycated haemoglobin (Glyc.Hb) and reduced levels of HD. Keywords: Type 2 diabetes mellitus, lipid profile, kidney function, liver function, glycated haemoglobin, fasting blood sugar.