A CLINICAL CASE OF COMPREHENSIVE REHABILITATION IN PATIENT WITH A COMORBID NEURODEGERATIVE AND AUTOIMMUNE DISEASES

N.I. Kholodkov, D.A. Dyachkov, О.А. Denisova, V.А. Drobyshev, I.A. Gobruseva, K.Е. Zueva, А.V. Shmal, А.R. Utyakov, А.I. Root, G.V. Meliksetov, K.V. Kozyr, I.E. Pochueva, N.V. Levchenko
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Abstract

Motor neuron disease, in the vast majority of cases occurring in the form of amyotrophic lateral sclerosis is a rare neurodegenerative disease with a prevalence of 2–3 cases per 100 thousand people in the population. The paper presents the results of a clinical observation of a patient with probable amyotrophic lateral sclerosis which occurs comorbidly with autoimmune myositis since the diagnosis was made in January 2023, as well as the effect of a comprehensive 21-day rehabilitation on clinical characteristics in the rehabilitation department of PARUS medical resort & SPA, LLC, near Novosibirsk. The individual rehabilitation course included physical rehabilitation, restorative training, apparatus physiotherapy and occupational therapy in addition to medication. By the end of the rehabilitation course, the indicators of the measured clinical scales improved: ALSFRS-R – by 3 times, MRC muscle strength – 2 times, Barthel – 2 times, Beck – 1.5 times, according to the walking scale of the Institute of Neurology – 1.3 times, paresis scale of the Institute of Neurology – 2 times, dysphagia – 4.5 times. The study allows expanding and supplementing the available data regarding the difficulty of verifying the diagnosis which directly affects the complexity of assessing the rehabilitation prognosis, setting rehabilitation goals and objectives in a patient with difficult to differentiate comorbid pathology.
神经退行性和自身免疫性疾病合并症患者综合康复一例
运动神经元疾病,在绝大多数情况下以肌萎缩侧索硬化症的形式发生,是一种罕见的神经退行性疾病,患病率为每10万人2-3例。本文报道一例自2023年1月确诊为肌萎缩侧索硬化症并合并自身免疫性肌炎的患者的临床观察结果,以及PARUS医疗度假村康复科21天综合康复对临床特征的影响;新西伯利亚附近的SPA有限责任公司。个别康复课程除药物治疗外,还包括身体康复、恢复性训练、器械物理治疗和职业治疗。康复疗程结束时,测量的临床量表指标:ALSFRS-R -提高3倍,MRC肌力- 2倍,Barthel - 2倍,Beck - 1.5倍,根据神经病学研究所步行量表- 1.3倍,神经病学研究所轻瘫量表- 2倍,吞咽困难- 4.5倍。该研究扩大和补充了关于诊断验证困难的现有数据,这直接影响了难以区分共病病理的患者评估康复预后、设定康复目标和目的的复杂性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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