Uterine leiomyoma in a 14 – year – old girl: Case report and literature review

Công Toàn Phạm, Thị Huệ Võ, Văn Hưng Nguyễn
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Abstract

Background: Uterine leiomyomas are benign tumors arising from the smooth muscle cells of the uterus or extracellular matrix, that are very common among women of reproductive age between 30 and 50 years of age. However, their incidence is extremely rare in women under 15-year-old (<1%) with unknown etiology. Ultrasound and magnetic resonance imaging (MRI) comfirms the location, number, size of mass, which plays an important role in prognosis and treatment. Leiomyomas have been managed in a variety of methods and are considered to decide the most optimal way to preserve fertility in adolescents. Case: A 14 year of age female patient was admitted with increased abdominal volume and pelvic mass over 6 months. Physical examination revealed the mass from the pelvic, corresponding in size to a pregnant uterus of 18 weeks (fundal height is 14cm). Ultrasound and MRI showed a uterine leiomyoma type 2 -5 (FIGO) and a differential diagnosis of leiomyosarcoma. The patient was managed successfully with complete tumor resection through abdominal myomectomy to preserve fertility. Histological results confirmed the final diagnosis was “benign degeneration of uterine leiomyoma”. Summary and conclusion: Although the occurrence of uterine leiomyomas in adolescents is very rare, this diagnosis is considered since a pelvic mass in this age group is discovered. Through rare but the differential diagnosis of uterine leiomyoma in the young population is leiomyosarcoma. Myomectomy is a suitable management to preserve fertility.
14岁女童子宫平滑肌瘤1例报告及文献复习
背景:子宫平滑肌瘤是发生于子宫平滑肌细胞或细胞外基质的良性肿瘤,常见于30 ~ 50岁育龄妇女。然而,在病因不明的15岁以下女性中发病率极低(1%)。超声和磁共振成像(MRI)确认肿块的位置、数量、大小,对预后和治疗起重要作用。平滑肌瘤有多种治疗方法,被认为是保留青少年生育能力的最佳方法。病例:一名14岁女性患者因腹部体积增加和盆腔肿块超过6个月而入院。体格检查显示肿块来自骨盆,大小相当于怀孕18周的子宫(子宫底高14cm)。超声及MRI示2 -5型子宫平滑肌瘤,鉴别诊断为平滑肌肉瘤。患者成功地通过腹部子宫肌瘤切除术完全切除肿瘤以保留生育能力。组织学结果证实最终诊断为“子宫平滑肌瘤良性变性”。摘要与结论:虽然子宫平滑肌瘤在青少年中的发生非常罕见,但由于在该年龄组中发现盆腔肿块,因此可以考虑这种诊断。通过对年轻人群中少见但鉴别诊断的子宫平滑肌瘤为平滑肌肉瘤。子宫肌瘤切除术是保持生育能力的合适方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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