Analysis of the activities of cord blood banks in the Russian Federation

Q4 Medicine

Genes and Cells Pub Date : 2023-10-03 DOI:10.23868/gc486812

Olga Tyumina, Stanislav Evgenievich Volchkov, Pavel Anatol'evich Ovchinnikov, Alexander Igorevich Bugakov, Ivan Viktorovich Porapov, Aleksandr Viktorovich Prihodko, Egor Mikhailovic Prihodko, Olga Vladimirovna Komarova

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引用次数: 0

Abstract

This review aimed to analyze the activities of all state and commercial cord blood banks in the Russian Federation, to estimate the total number of cord blood samples in storage at the beginning of 2023, and to determine the practical use of the biomaterial for treatment allogeneic and autologous transplants for oncohematological diseases, as well as for scientific research in the field of regenerative medicine for the entire period of the banks' operation, which is twenty years. To date, there are 12 cord blood banks providing personal, public or mixed storage of samples. At the moment, up to 26,000 cord blood samples are in public storage, and about 75,000 samples are in personal storage. As part of the review, the main and additional services provided by banks, as well as their current cost, were studied. The average cost of cord blood sample collection in the Russian Federation is 62,500 rubles, and the average annual cost of storage is 6,000 rubles. The main market indicators, trends, key problems of biobanking and prospects for the use of cord blood cells in the Russian Federation in the coming years are considered in detail. Separately, data on the prospects for the use of umbilical cord mesenchymal stem cells, a widely studied biomaterial, which, like cord blood, can be collected after childbirth and cryopreserved for long-term storage, are briefly presented. Stem cells of the umbilical cord are being actively studied in the field of regenerative medicine due to their properties to restore cartilaginous muscle and bone tissue, stimulate the growth of new blood vessels, and block autoimmune reactions. In addition, the current tasks and results of the activities of Ruscord, an association of specialists and organizations in the field of procurement, storage, use of cord blood cells and cell technologies, which over several years of its activity has already made a significant contribution to the development of the biobanking market, were analyzed. In September 2020, a unified standard for the collection, processing, storage and issuance of cord blood for use was approved the Russian standard RUSCORD.

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俄罗斯联邦脐带血银行活动分析

本次审查的目的是分析俄罗斯联邦所有国家和商业脐带血库的活动，估计2023年初储存的脐带血样本总数，并确定在整个脐带血库运营期间(即20年)，这种生物材料用于治疗肿瘤血液疾病的同种异体和自体移植以及用于再生医学领域的科学研究的实际用途。迄今为止，有12个脐带血库提供个人、公共或混合储存样本。目前，多达2.6万份脐带血样本在公共储存处，约7.5万份样本在个人储存处。作为审查的一部分，研究了银行提供的主要和额外服务及其目前的费用。在俄罗斯联邦，脐带血样本采集的平均费用为62,500卢布，平均每年的储存费用为6,000卢布。详细审议了俄罗斯联邦未来几年生物银行的主要市场指标、趋势、关键问题和使用脐带血细胞的前景。另外，简要介绍了脐带间充质干细胞应用前景的数据。脐带间充质干细胞是一种广泛研究的生物材料，与脐带血一样，可以在分娩后收集并冷冻保存以长期储存。由于脐带干细胞具有恢复软骨肌肉和骨组织、刺激新血管生长和阻断自身免疫反应的特性，因此在再生医学领域正受到积极的研究。此外，还分析了Ruscord目前的任务和活动结果，Ruscord是采购、储存、使用脐带血细胞和细胞技术领域的专家和组织协会，其活动在几年的时间里已经对生物银行市场的发展做出了重大贡献。2020年9月，俄罗斯标准RUSCORD批准了用于采集、处理、储存和发放脐带血的统一标准。

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来源期刊

Genes and Cells Medicine-Transplantation

CiteScore

0.50

自引率

0.00%

发文量

期刊介绍： “Genes and Cells” (the old name is “Cell Transplantology and Tissue Engineering”) is a peer-reviewed scientific and practical journal recommended by the Higher Attestation Commission of the Ministry of Education and Science of the Russian Federation for publishing basic materials of dissertation research. Originally conceived as a highly specialized publication, the Journal has now gained an ever wider target audience. If at the beginning of its journey — from September 2005 — the target audience of the journal were biotechnologists, specialists in the field of molecular and cell biology, by now it has expanded with medical practitioners. Such progressive dynamics are absolutely natural — over the last 7-10 years, biomedical technologies have come out of the exotic category, lack of understanding of the inhabitants and mistrust of clinicians have been replaced by interest and awareness of the need to use biotechnology tools in medicine no longer tomorrow, but today. The sections of the journal are formulated to fully disclose the target topics of the publication, convey to readers the opinions of leading experts in the field of biomedical technologies on topical issues of concern, acquaint them with the most significant recent foreign and domestic research, materials of thematic conferences, present analytical information on fundamental issues of biomedical technologies trends in the biotech business. The journal includes the following headings: “expert opinions”, “cell technology news”, “reviews”, “original research”, “clinical experience”, “discussion and general theoretical work”, “stem cell business”.