Molar pregnancy with a co-exist normal viable fetus and successful pregnancy outcome: a case report

Q4 Medicine
Nasrin Hossain, Faria Anjuman, Mohammod Sharif Mahmud, Shamin Hossain
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Abstract

Background: Co-existence of a hydatidiform mole with a normal fetus is extremely rare and is considered as a high risk pregnancy. Methods: It was an observational study conducted during July 2020 to march 2021 Case report: A 23 year old primigravida, referred with a diagnosis of 27 weeks pregnancy with gestational choriocarcinoma. She was booked patient. USG report at 9 weeks with a single gestational sac and single fetal pole. Her complains were lower abdominal pain and brownish vaginal discharge. Thoroughly evaluated the patient to exclude distal metastasis. Serum Beta HCG was 3,23,280 IU/L. USG and fetal MRI report were single graved fetus, no anomaly detected and a large hyper echogenic soft tissue mass (10*7cm) interposed with multiple tiny cystic spaces near to placenta. Diagnosis was 28 weeks pregnancy with partial mole and high rising β HCG level. Proper counseling, the pregnancy was continued as per the patient’s desire. The pregnancy was closely monitored with serial serum β HCG, and USG. Spontaneously labour pain start at 36 weeks pregnancy and delivered a live baby per vaginally at 36 weeks with near normal Apgar score. The placenta with molar tissue was sent for histopathological examination. The histopathologically confirmed partial mole with normal placenta. Beta HCG was 20,000 ml/L at 7 days and normal at 8 weeks after delivery. Close surveillance for 6 months. After 6 month follow-up, both mother and development of her baby are alright. Conclusion: The diagnosis, management and monitoring of this condition will remain challenging because of its rarity. Though the general trend is to terminate pregnancy with coexistent mole in anticipation of complications, under close surveillance, optimal outcomes can be achieved. Bangladesh Medical Res Counc Bull 2022; 48(3): 249-253
磨牙妊娠同时存在正常存活胎儿和成功妊娠结局:1例报告
背景:葡萄胎与正常胎儿共存极为罕见,被认为是高危妊娠。方法:这是一项观察性研究,于2020年7月至2021年3月进行。病例报告:一名23岁的初产妇,诊断为妊娠27周,妊娠绒毛膜癌。她是预约病人。USG报告在9周单胎囊和单胎极。她的主诉是下腹疼痛和带褐色阴道分泌物。彻底评估患者以排除远端转移。血清β - HCG为3,23,280 IU/L。USG和胎儿MRI报告为单胎,未发现异常,胎盘附近有一个大的高回声软组织肿块(10*7cm),其间有多个微小囊性间隙。诊断:妊娠28周,部分痣,β - HCG升高。在适当的咨询下,怀孕按照病人的意愿继续进行。采用连续血清β - HCG、USG监测妊娠情况。妊娠36周时自然阵痛开始,36周时单次阴道分娩一名活婴,Apgar评分接近正常。带磨牙组织的胎盘送组织病理学检查。组织病理学证实部分痣,胎盘正常。产后7天β HCG为20000 ml/L, 8周正常。密切监测6个月。经过6个月的随访,母亲和婴儿发育正常。结论:本病罕见,诊断、治疗和监测仍具有挑战性。虽然普遍的趋势是终止妊娠共存痣预期并发症,密切监测下,可以达到最佳结果。孟加拉国医疗援助理事会2022年公报;48 (3): 249 - 253
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来源期刊
CiteScore
0.30
自引率
0.00%
发文量
48
期刊介绍: The official publication of the Bangladesh Medical Research Council.
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