MOLECULAR MECHANISMS OF OBESITY: A REVIEW OF THE MOST RELEVANT GENE MARKERS

Q4 Medicine

Genes and Cells Pub Date : 2023-05-30 DOI:10.23868/gc375313

Sergey Karabanov

引用次数: 0

Abstract

The development of genome-wide association studies has made it possible to isolate many genes associated with obesity — one of the most common diseases in the world. For a possible correction of this process, there is a need for a more detailed study of certain genes, the expression of which can change during metabolic processes associated with obesity. The aim of this review is to identify the most promising candidate genes for further studies of metabolic disorders associated with obesity.

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肥胖的分子机制:最相关的基因标记的综述

全基因组关联研究的发展使得分离许多与肥胖相关的基因成为可能。这是世界上最常见的疾病之一。为了可能纠正这一过程，需要对某些基因进行更详细的研究，这些基因的表达在与肥胖相关的代谢过程中会发生变化。本综述的目的是确定最有希望的候选基因，以进一步研究与肥胖相关的代谢紊乱。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Genes and Cells Medicine-Transplantation

CiteScore

0.50

自引率

0.00%

发文量

期刊介绍： “Genes and Cells” (the old name is “Cell Transplantology and Tissue Engineering”) is a peer-reviewed scientific and practical journal recommended by the Higher Attestation Commission of the Ministry of Education and Science of the Russian Federation for publishing basic materials of dissertation research. Originally conceived as a highly specialized publication, the Journal has now gained an ever wider target audience. If at the beginning of its journey — from September 2005 — the target audience of the journal were biotechnologists, specialists in the field of molecular and cell biology, by now it has expanded with medical practitioners. Such progressive dynamics are absolutely natural — over the last 7-10 years, biomedical technologies have come out of the exotic category, lack of understanding of the inhabitants and mistrust of clinicians have been replaced by interest and awareness of the need to use biotechnology tools in medicine no longer tomorrow, but today. The sections of the journal are formulated to fully disclose the target topics of the publication, convey to readers the opinions of leading experts in the field of biomedical technologies on topical issues of concern, acquaint them with the most significant recent foreign and domestic research, materials of thematic conferences, present analytical information on fundamental issues of biomedical technologies trends in the biotech business. The journal includes the following headings: “expert opinions”, “cell technology news”, “reviews”, “original research”, “clinical experience”, “discussion and general theoretical work”, “stem cell business”.