Lina Livrinska, Teodora Tasevska, Dushko Shalabalija, Ljubica Mihailova, Marija Glavash Dodov, Radmil Polenakovikj, Trajche Velkovski, Maja Simonoska Crcarevska
{"title":"Effect of calcium chloride on physical properties of blended alginate carboxymethyl cellulose wound dressings","authors":"Lina Livrinska, Teodora Tasevska, Dushko Shalabalija, Ljubica Mihailova, Marija Glavash Dodov, Radmil Polenakovikj, Trajche Velkovski, Maja Simonoska Crcarevska","doi":"10.33320/maced.pharm.bull.2023.69.03.144","DOIUrl":null,"url":null,"abstract":"Natural polymers have been used for a variety of biomedical and pharmaceutical applications due to their resemblance of extracellular matrix components. One of these applications is the use of polysaccharides in the fabrication of film wound dressings. Since alginate exhibits excellent film forming properties, in addition to its biocompatibility, it has been used in this research as a primary polymer, alongside with carboxymethyl cellulose. The addition of another polymer, as well as the process of crosslinking, are usual modifications made for the purpose of improving the physical and biological properties of alginate films (Aravamudhan et al.,2014). The aim of this study was to showcase the effect of cationic crosslinking on physical properties of blended alginate carboxymethyl cellulose wound dressing.","PeriodicalId":30550,"journal":{"name":"Makedonsko Farmacevtski Bilten","volume":"6 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Makedonsko Farmacevtski Bilten","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33320/maced.pharm.bull.2023.69.03.144","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Natural polymers have been used for a variety of biomedical and pharmaceutical applications due to their resemblance of extracellular matrix components. One of these applications is the use of polysaccharides in the fabrication of film wound dressings. Since alginate exhibits excellent film forming properties, in addition to its biocompatibility, it has been used in this research as a primary polymer, alongside with carboxymethyl cellulose. The addition of another polymer, as well as the process of crosslinking, are usual modifications made for the purpose of improving the physical and biological properties of alginate films (Aravamudhan et al.,2014). The aim of this study was to showcase the effect of cationic crosslinking on physical properties of blended alginate carboxymethyl cellulose wound dressing.