Impact of Gastroesophageal Reflux Disease on Patients Undergoing Lung Transplantation for COVID-19: A Single Institution Retrospective Study

Journal of current surgery Pub Date : 2023-09-01 DOI:10.14740/jcs467

Christopher Kim, Daniel Bushyhead, Edward Chan, Howard Huang, Ray Chihara, Ahmad Goodarzi, Simon Yau, Jihad Youssef, Thomas Macgillivray, Erik Suarez, Philip Chou, Gulchin Ergun

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Abstract

Background: Patients with coronavirus disease 2019 (COVID-19)-associated respiratory failure undergoing lung transplantation is an emerging subset of transplant patients in which gastroesophageal reflux disease (GERD) pre- or post-transplant is not well characterized. Methods: We retrospectively evaluated patients undergoing lung transplant for COVID-19, with attention to pre- and post-operative physiological testing for GERD. Results: Seventeen patients were identified who had undergone lung transplant for COVID-19. No patient underwent pre-transplant GERD testing. Post-transplant, 70.5% (12/17) patients reported reflux symptoms confirmed with additional testing. Three patients underwent anti-reflux surgery (ARS) based on results of testing, and none had complications or symptom-based recurrence of reflux. Conclusion: Our study depicts a unique cohort of patients who were unable to undergo pre-transplant testing for GERD in the setting of a global pandemic, and who were routinely assessed and managed post-transplant. J Curr Surg. 2023;13(1):12-16 doi: https://doi.org/10.14740/jcs467

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胃食管反流病对COVID-19患者肺移植的影响:一项单机构回顾性研究

背景:接受肺移植的冠状病毒病2019 (COVID-19)相关呼吸衰竭患者是一个新兴的移植患者亚群，其中胃食管反流病(GERD)在移植前或移植后没有很好的特征。方法:我们回顾性评估因COVID-19接受肺移植的患者，并注意术前和术后GERD的生理检查。结果:17例新冠肺炎患者行肺移植手术。没有患者接受移植前GERD检测。移植后，70.5%(12/17)患者报告的反流症状经额外检测证实。3例患者根据检测结果接受了抗反流手术(ARS)，无并发症或症状性反流复发。结论:我们的研究描述了一组独特的患者，他们在全球大流行的背景下无法进行GERD的移植前检测，并且在移植后进行了常规评估和管理。中华实用外科杂志;2013;13(1):12-16 doi: https://doi.org/10.14740/jcs467

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Journal of current surgery

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