Trichomonas vaginalis and human papillomavirus: Association with the microbiota and burden on the cervix

Q4 Medicine

Gynecology and Obstetrics Clinical Medicine Pub Date : 2023-12-01 DOI:10.1016/j.gocm.2023.10.002

Kelvin Stefan Osafo , Wenyu Lin , Binhua Dong , Pengming Sun

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引用次数: 0

Abstract

Trichomoniasis and HPV infection are common non-viral and viral sexually transmitted diseases worldwide. Emerging evidence shows that the female genital tract and its microbiota are greatly affected by these pathogens. However, the relationship between Trichomonas vaginalis, the vaginal microbiome, and High-risk (HR)-HPV infection is complex and multifaceted. Studies have proven that concurrent infections of HIV and HPV increase the risk of cervical cancer. With this basis, a question arises: How does the concurrent infection of trichomonas vaginalis and HPV affect genital tract health? Does this concurrent infection enhance or inhibit the development of cervical lesions? This review aims to bring light to these questions. This review also covers the association of trichomonas vaginalis and HPV with the microbiota of the genital tract.

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阴道毛滴虫和人类乳头瘤病毒：与微生物群和宫颈负担的关系

滴虫病和人乳头瘤病毒感染是全球常见的非病毒性和病毒性性传播疾病。新的证据表明，女性生殖道及其微生物群受到这些病原体的极大影响。然而，阴道毛滴虫、阴道微生物群和高危（HR）-HPV 感染之间的关系是复杂和多方面的。研究证明，同时感染 HIV 和 HPV 会增加罹患宫颈癌的风险。在此基础上，就产生了一个问题：同时感染阴道毛滴虫和 HPV 对生殖道健康有何影响？同时感染会增强还是抑制宫颈病变的发展？本综述旨在揭示这些问题。本综述还涉及阴道毛滴虫和人乳头瘤病毒与生殖道微生物群的关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Gynecology and Obstetrics Clinical Medicine Medicine-Obstetrics and Gynecology

CiteScore

0.70

自引率

0.00%

发文量

审稿时长

18 weeks