Endotype Conformity with Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis (JESREC) Score in Chronic Rhinosinusitis

Q4 Medicine

Egyptian Journal of Ear, Nose, Throat and Allied Sciences Pub Date : 2023-01-01 DOI:10.21608/ejentas.2023.185570.1600

Iriana Maharani, Finna Christianty, Edi Handoko, Nanik Setijowati

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引用次数: 0

Abstract

Introduction: Chronic rhinosinusitis (CRS) is one of the most prevalent disease entities in ORL-HNS field. Management strategy of CRS remains challenging among otorhinolaryngologist. Currently, CRS was known as a heterogeneous disease with various endotypes and phenotypes. By identifying endotypes, comprehensive management strategy in CRS was expected. The Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis (JESREC) score was a categorical score developed from Japan to diagnose eosinophilic chronic rhinosinusitis (eCRS) and non-eosinophilic chronic rhinosinusitis (non-eCRS). The assessment of JESREC score was expected to have conformity with CRS endotypes so that it can be used as future efficient diagnostic modality. Objective: This study aims to determine conformity and accuracy of endotype with JESREC score. Patients and Methods: An analytic study with a cross-sectional design involving 33 samples of primary CRS. Biomarker for specific endotypes measured by ELISA. Results: Statistical analysis with Mc. Nemar showed no difference/ a conformity between JESREC score and CRS endotypes ( p>0.05 ) with sensitivity 61,5% and specificity 90%. Conclusion: JESREC score is considered a screening modality for CRS endotype.

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慢性鼻窦炎患者难治性嗜酸性粒细胞慢性鼻窦炎(JESREC)评分的内型与日本流行病学调查相符

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来源期刊

Egyptian Journal of Ear, Nose, Throat and Allied Sciences Medicine-Otorhinolaryngology

CiteScore

0.20

自引率

0.00%

发文量

期刊介绍： Egyptian Journal of Ear, Nose, Throat and Allied Sciences aspires to play a national, regional and international role in the promotion of responsible and effective research in the field of Otolaryngology, Head and Neck Surgery in Egypt, Middle East and Africa. Mission To encourage and support research in Ear, Nose and Throat (ENT) field and interdisciplinary topics To implement high-quality editorial practices among Otolaryngologists To upgrade the ability and experience of local doctors in international publishing To offer professional publishing support to local researchers, creating a supportive network for career development To highlight ENT diseases and problems peculiar to our region To promote research in endemic, hereditary and infectious ENT problems related to our region To expose and study impact of ethnic, social, environmental and cultural issues on expression of different ENT diseases To organize common epidemiologic research of value to the region To provide resource to national and regional authorities about problems in the field of ENT and their implication on public health and resources To facilitate exchange of knowledge in our part of the world To expand activities with regional and international scientific societies.