Efficacy of Peroral Endoscopic Myotomy for Achalasia: Evaluation of Treatment Effect using Timed Barium Esophagography

IF 0.5 4区 农林科学 Q4 FORESTRY
Sylwan Pub Date : 2023-01-01 DOI:10.59879/4ppre
Jae-Joon Chung, Eun-Suk Cho, Joo Hee Kim
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引用次数: 0

Abstract

Peroral endoscopic myotomy (POEM) is one of the standard treatment modality for achalasia. This study was to evaluate the usefulness of timed barium esophagography (TBE) in the evaluation of treatment effect of POEM for achalasia. A total of 36 patients (M:F=22:14) underwent pre- and post-POEM TBE (3 groups according to lower esophageal sphincter (LES) caliber, A: < 5 mm, B: 5~8 mm, C: > 8 mm). On pre and post-POEM TBE, the rate of area changes of barium column and the changes of LES caliber were investigated. All data were statistically analyzed using the Kruskal-Wallis test or Mann-Whitney U test. The mean rate of area change of the barium column at 5 minutes between pre- and post-POEM TBE were -51.7%, -28.8% and -11.6% in group A (n=10), B (n=18), and C (n=8), respectively, statistically significant (p < 0.001). The rate difference of the barium column area changes between group A and group B only showed the statistical significance (p < 0.001). The mean increased caliber of LES after POEM was 5.5 mm, 2.9 mm, and 3.3 mm in group A, B, and C, respectively. Group A and bird’s beak type showed a statistically significant treatment effect (p < 0.001). In conclusion, TBE was useful in the evaluation of the treatment effect of POEM for achalasia and the narrowest LES group and bird’s beak esophageal type on TBE showed statistically significant treatment effects.
经口内镜下肌切开术治疗贲门失弛缓症的疗效:定时钡餐食管造影治疗效果评价
经口内窥镜肌切开术(POEM)是贲门失弛缓症的标准治疗方式之一。本研究旨在评价定时钡餐食管造影(TBE)在评价POEM治疗贲门失弛缓症疗效中的作用。共36例患者(M:F=22:14)行poem术前和术后TBE(按食管下括约肌(LES)口径分3组,A: <5 mm, B: 5~ 8mm, C: >8毫米)。在poem - TBE前后,考察了钡柱面积变化率和LES口径的变化。所有数据采用Kruskal-Wallis检验或Mann-Whitney U检验进行统计学分析。A组(n=10)、B组(n=18)、C组(n=8)的平均5分钟钡柱面积变化率分别为-51.7%、-28.8%、-11.6%,差异均有统计学意义(p <0.001)。A组与B组间钡柱面积变化率差异仅具有统计学意义(p <0.001)。A组、B组、C组经POEM治疗后LES平均口径增加5.5 mm、2.9 mm、3.3 mm。A组和鸟喙型治疗效果有统计学意义(p <0.001)。综上所述,TBE可用于评价POEM对贲门失弛缓症的治疗效果,最窄LES组和鸟嘴食管型对TBE的治疗效果有统计学意义。
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来源期刊
Sylwan
Sylwan 农林科学-林学
CiteScore
0.70
自引率
16.70%
发文量
0
审稿时长
1 months
期刊介绍: SYLWAN jest najstarszym w Polsce leśnym czasopismem naukowym, jednym z pierwszych na świecie. Został założony w 1820 roku w Warszawie. Przyczynił się w znakomity sposób do rozwoju polskiego leśnictwa, służąc postępowi, upowszechnieniu wiedzy leśnej oraz rozwojowi nauki.
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