{"title":"Clinical Utility of Porphyrin Metabolic Pathway-based Fluorescent Urine Cytology in Urothelial Carcinoma","authors":"Makito Miyake, Yasushi Nakai, Kiyohide Fujimoto","doi":"10.2530/jslsm.jslsm-44_0041","DOIUrl":null,"url":null,"abstract":"近年の泌尿生殖器系悪性腫瘍における光力学的診断技術の導入は目覚ましい.2017年12月,筋層浸潤性膀胱癌の経尿道的手術時の可視化・ナビゲーションのための診断薬としてアミノレブリン酸塩酸塩が本邦で保険承認された.我々は,筋層非浸潤性膀胱癌治療後の経過観察の簡便化かつ低侵襲化を目標に,ポルフィリン代謝経路利用蛍光尿細胞診を開発してきたので,その経緯,現状,展望を紹介する.","PeriodicalId":19350,"journal":{"name":"Nippon Laser Igakkaishi","volume":"32 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nippon Laser Igakkaishi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2530/jslsm.jslsm-44_0041","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
基于卟啉代谢途径的荧光尿细胞学在尿路上皮癌中的临床应用
近年来,光动力诊断技术在泌尿生殖系统恶性肿瘤中的应用取得了显著进展。2017年12月,作为肌层浸润性膀胱癌经尿道手术时可视化、导航的诊断药,氨基左左酸盐酸盐在日本获得保险批准。我们以肌层非浸润性膀胱癌治疗后的随访简便化和微创化为目标,开发了利用卟啉代谢途径的荧光尿细胞诊断,介绍其经过、现状和展望。
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