Approaches to predicting life expectancy in elderly coronary artery disease patients with comorbid conditions

E. O. Asanov, G. P. Voinarovska, I. A. Dyba
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Abstract

The aim of the study was to develop a model for predicting the probability of survival up to 80 years of age for elderly and senile patients with coronary artery disease (CAD) and concomitant conditions. Materials and methods. A retrospective data analysis of elderly and senile CAD patients who were observed in the period 1997–2019 and died from a cardiovascular event. Results. Using binary logistic regression analysis, a model of the survival probability up to 80 years in CAD patients with comorbid conditions has been developed. The overall accuracy of the model was 83.12 % (χ2 = 6.70, p < 0.05), and the predictive accuracy of the model (AUC = 0.853, 95 % CI 0.802–0.896) was sufficiently high and adequate to use in clinical practice. Odds ratio has shown a greater contribution of arterial hypertension and diabetes mellitus to reduced probabilities of surviving to the age of 80, a less significant contribution – of chronic obstructive pulmonary disease and dyslipidemia. Conclusions. The developed model for predicting the survival probability up to 80 years for older age group patients with coronary artery disease and comorbid conditions can be used to evaluate the effectiveness and correct medical and preventive measures.
有合并症的老年冠心病患者预期寿命的预测方法
该研究的目的是建立一个模型,用于预测老年和老年冠心病(CAD)及伴随疾病患者存活至80岁的概率。材料和方法。回顾性分析1997-2019年期间观察到的死于心血管事件的老年和老年CAD患者的数据。结果。采用二元logistic回归分析,建立了伴有合并症的冠心病患者80年生存率模型。模型的总体准确率为83.12% (χ2 = 6.70, p <0.05),模型的预测准确率(AUC = 0.853, 95% CI 0.802 ~ 0.896)足够高,可用于临床实践。优势比显示,动脉高血压和糖尿病对80岁生存率降低的贡献较大,而慢性阻塞性肺病和血脂异常的贡献较小。结论。所建立的预测老年冠心病及合并症患者80岁生存率的模型可用于评估治疗和预防措施的有效性和正确性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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