N, S, Br co-doped carbon dots: One-step synthesis and fluorescent detection of 6-mercaptopurine in tablet

IF 6.1 1区医学 Q1 PHARMACOLOGY & PHARMACY

Journal of Pharmaceutical Analysis Pub Date : 2023-11-01 DOI:10.1016/j.jpha.2023.11.001

Qi Wang, Ying Cheng, Lifeng Ding, Shengling Li, Jie Zhang, Yulan Niu, Ziye Jing

引用次数: 0

Abstract

Scheme of synthesis of N, S, Br-CDs and fluorescent detection of 6-MP. • A suitable detection method for 6-mercaptopurine (6-MP) was developed. • N, S, Br-carbon dots (N, S, Br-CDs) synthesized by one-step hydrothermal method. • The as-synthesized N, S, Br-CDs exhibited favorable fluorescence. • The fluorescence intensity of the N, S, Br-CDs was quenched by 6-MP. • The developed method is suitable for detecting 6-MP in real pharmaceutical samples.

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N、S、Br共掺杂碳点:片剂中6-巯基嘌呤的一步合成及荧光检测

N, S, Br-CDs的合成方案及6-MP的荧光检测。•建立了6-巯基嘌呤(6-MP)的检测方法。•一步水热法合成N, S, br -碳点(N, S, Br-CDs)•合成的N, S, Br-CDs具有良好的荧光特性。•6-MP猝灭N, S, Br-CDs的荧光强度。•该方法适用于实际药物样品中6-MP的检测。

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来源期刊

Journal of Pharmaceutical Analysis Chemistry-Electrochemistry

CiteScore

16.20

自引率

2.30%

发文量

674

审稿时长

22 weeks

期刊介绍： The Journal of Pharmaceutical Analysis (JPA), established in 2011, serves as the official publication of Xi'an Jiaotong University. JPA is a monthly, peer-reviewed, open-access journal dedicated to disseminating noteworthy original research articles, review papers, short communications, news, research highlights, and editorials in the realm of Pharmacy Analysis. Encompassing a wide spectrum of topics, including Pharmaceutical Analysis, Analytical Techniques and Methods, Pharmacology, Metabolism, Drug Delivery, Cellular Imaging & Analysis, Natural Products, and Biosensing, JPA provides a comprehensive platform for scholarly discourse and innovation in the field.