PO105

Abstract

There are few approaches in treatment of non-melanoma skin cancer: operation, external irradiation, brachytherapy, use of appropriate medications. In brachytherapy it is possible to use rigid needles, flexible applicators and application methods. As a rule the choice depends on many factors - size of the tumor, location, histology, previous treatments etc. Purpose The aim of the work was to evaluate the effectiveness of applicator method in brachytherapy of non melanoma skin cancer. In this report we evaluate the results of the application method in treatment of non melanoma skin cancer. Patients and Methods 86 patients have been treated since 2017 till 2020 years. Basalioma was diagnosed in 59 pts, squamous cell carcinoma - in 27 pts. 47 pts had tumor in head and neck region, 21 - in different sites of the body and 18 - in limbs. 9 pts had recurrence after operation. The location of the applicators was chosen individually, they were attached to an individual mask that repeats the curves of the body and provides a rigid fixation of the applicators during treatment. Total dose amounted to 36 Gy (6 Gy * 6 fraction, 1 fraction per day) . The dose planning was performed at Oncentra 4.0. Treatment was fulfilled at Microselectron (30 channels) HDR. Planning was done on the basis of CT images. Dose normalisation depended on many factors and ranged from 3 mm till 10 mm if there was a necessity. As a rule, reaction to irradiation began at different times after the start of treatment but the peak of reactions usually happens in approximately 10 days after treatment completion and were strongly dealt with the tumor location. Results The healing lasted for three months on average. As a result in 83 patients (97%) the treatment effect was good: full tumor regression with good cosmetic effect. In 3 patients prolongacion morbi was observed and tumor was reirradiated. During the first year patients were under control every 3 months and later - every 6 months. Conclusion With the correct choice of application method, the results of the treatment of non-melanoma cancer can be considered as good. There are few approaches in treatment of non-melanoma skin cancer: operation, external irradiation, brachytherapy, use of appropriate medications. In brachytherapy it is possible to use rigid needles, flexible applicators and application methods. As a rule the choice depends on many factors - size of the tumor, location, histology, previous treatments etc. The aim of the work was to evaluate the effectiveness of applicator method in brachytherapy of non melanoma skin cancer. In this report we evaluate the results of the application method in treatment of non melanoma skin cancer. 86 patients have been treated since 2017 till 2020 years. Basalioma was diagnosed in 59 pts, squamous cell carcinoma - in 27 pts. 47 pts had tumor in head and neck region, 21 - in different sites of the body and 18 - in limbs. 9 pts had recurrence after operation. The location of the applicators was chosen individually, they were attached to an individual mask that repeats the curves of the body and provides a rigid fixation of the applicators during treatment. Total dose amounted to 36 Gy (6 Gy * 6 fraction, 1 fraction per day) . The dose planning was performed at Oncentra 4.0. Treatment was fulfilled at Microselectron (30 channels) HDR. Planning was done on the basis of CT images. Dose normalisation depended on many factors and ranged from 3 mm till 10 mm if there was a necessity. As a rule, reaction to irradiation began at different times after the start of treatment but the peak of reactions usually happens in approximately 10 days after treatment completion and were strongly dealt with the tumor location. The healing lasted for three months on average. As a result in 83 patients (97%) the treatment effect was good: full tumor regression with good cosmetic effect. In 3 patients prolongacion morbi was observed and tumor was reirradiated. During the first year patients were under control every 3 months and later - every 6 months. With the correct choice of application method, the results of the treatment of non-melanoma cancer can be considered as good.