Winward Choy , Tej D Azad , Justin K Scheer , Michael M Safaee , Christopher P Ames
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引用次数: 0
Abstract
Outcomes following adult spinal deformity (ASD) surgery vary, despite technical advances and improved patient selection. Current prediction models, comprised of clinical and radiographic parameters, do not fully explain observed variation in patient outcomes. Objective biomarkers have fundamentally improved prediction, prognostication, and risk-stratification in other disease states and warrant further exploration in the care of ASD patients. In this review, we provide an overview of the need for objective biomarkers in the management of ASD. We detail advances in biomarker development for patient frailty, biological age, sarcopenia, bone quality, and nutritional status and consider how these biomarkers might be integrated into the management of ASD patients.
期刊介绍：
Seminars in Spine Surgery is a continuing source of current, clinical information for practicing surgeons. Under the direction of a specially selected guest editor, each issue addresses a single topic in the management and care of patients. Topics covered in each issue include basic anatomy, pathophysiology, clinical presentation, management options and follow-up of the condition under consideration. The journal also features "Spinescope," a special section providing summaries of articles from other journals that are of relevance to the understanding of ongoing research related to the treatment of spinal disorders.
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