Gastrointestinal Dependent Stromal Tumor of the Small Intestine (Ileum): Case Report and Literature Review

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Abstract

Introduction: The cells of Gastrointestinal Tumors show characteristics similar to those of the interstitial cells of Cajal, which play a neuromotor role in the regulation of normal intestinal motility. Clinical case: A 57-year-old female patient came to our service for abdominal pain accompanied by abdominal pain in the hypogastrium for 3 months. The pathological anatomy reports a tumor measuring 4 cm by 3 cm by 2 cm, 20 cm from the ileocecal valve. With a spindle cell pattern, in the immunohistochemical study it presents c-kit (+) and CD 34 (+), with a mitosis index < 5 per 50 field, it is considered low risk. He was referred to the medical oncology service, which decided on adjuvant treatment with imatinib mesylate. Discussion: GISTs are usually incidental findings diagnosed during other operations. These are mostly operations due to malignancies of other dignities.Conclusions: Patients with GIST showed a surprising frequency of coincidences with other benign or malignant tumors.
小肠(回肠)胃肠道依赖性间质瘤:病例报告及文献复习
胃肠道肿瘤细胞表现出与Cajal间质细胞相似的特征,在调节正常肠道运动中发挥神经运动作用。临床病例:一名57岁女性患者因腹痛伴下腹部疼痛3个月来我院就诊。病理解剖报告肿瘤大小为4cm × 3cm × 2cm,距回盲瓣20cm。呈梭形细胞模式,免疫组化研究显示c-kit(+)和cd34(+),有丝分裂指数<5 / 50,被认为是低风险。他被转介到肿瘤内科服务,该服务决定用甲磺酸伊马替尼辅助治疗。讨论:gist通常是在其他手术中偶然发现的。这些手术大多是由于其他尊严的恶性肿瘤。结论:GIST患者与其他良恶性肿瘤的重合率高得惊人。
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