An Unusual Presentation of Huge Gastric Cystic Gastrointestinal Stromal Tumor

Nihan TURHAN, Didem ERTORUL, Elbrus ZARBALİYEV, Safak COSKUN, Dilek YILMAZ
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Abstract

Gastrointestinal stromal tumors (GISTs), nonepithelial, mesenchymal tumors arising from the interstitial cells of Cajal. The diagnostic tool for the GISTs is tyrosine kinase growth factor receptor (c-KIT / CD117) expression. They most commonly occur in the the stomach. Here we reported a rare case of GIST, presenting as a large cystic mass connected to the main tumor with a peduncle. A 44-year-old female patient presented to the emergency department with abdominal pain and intestinal obstruction. Emergency laparatomy revealed a cystic mass of approximately 25 cm in diameter. The pathological diagnosis was gastrointestinal stromal tumor with cystic degenaration. Tumor contained areas of necrosis, high mitotic index, c-KIT positive and was large in diameter. Cystic GISTs have poor prognostic factors and patients should be followed closely in the postoperative period.
巨大胃囊性胃肠道间质瘤的罕见表现
胃肠道间质肿瘤(gist),由Cajal间质细胞引起的非上皮间质肿瘤。gist的诊断工具是酪氨酸激酶生长因子受体(c-KIT / CD117)的表达。它们最常发生在胃部。这里我们报告一个罕见的GIST病例,表现为一个大的囊性肿块,与主要肿瘤相连,有一个结节。女,44岁,因腹痛、肠梗阻就诊于急诊科。急诊腹腔镜检查发现一个直径约25厘米的囊性肿块。病理诊断为胃肠道间质瘤伴囊性变性。肿瘤内有坏死区,有丝分裂指数高,c-KIT阳性,直径大。囊性胃肠道间质瘤预后不良,术后应密切随访。
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