Severe HELLP Syndrome Complicated by Multiorgan Impairment and DIC: The Role of Drain Placement: A Case Report

Xenofontas Bazoukis, Alkistis Victoros Khristianov, Giannis Pavlides, Athanasios Chasiotis, Ioannis Kazakos
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Abstract

Background: Disseminated intravascular coagulation (DIC) can present postpartumly in women with hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome. This report highlights the importance of drain insertion following emergency cesarean section in anticipation of DIC. This would avoid the need of an open exploratory laparotomy procedure. Case: At 34 weeks of gestation, a P1G4 woman was diagnosed with severe pre-eclampsia and HELLP syndrome and her baby with intrauterine growth restriction (IUGR) and fetal distress. The woman received hydralazine, labetalol, methyl-dopa, magnesium sulphate and an emergency cesarean section was performed. A few hours later, the woman developed DIC. Red blood cells (RBC), fresh frozen plasma (FFP) and platelets (PLTs) were administered and an abdominal CT was performed, revealing intra-abdominal and anterior rectus sheath haematomas. An open exploratory laparotomy was performed to identify areas of bleeding and a drain was inserted to monitor the bleeding. The woman was closely monitored and regained haemodynamic stability. Conclusion: DIC is a common postpartum complication in women diagnosed with HELLP syndrome. Preemptive drain insertion following cesarean section in these women could avoid the need for additional revision surgery should DIC occur. Clear guidelines on the topic are lacking. Teaching Points: Postpartum surgical drain placement in women diagnosed with HELLP syndrome who later develop DIC could avoid the need of additional surgery. Precis Preemptively placing a surgical drain following cesarean section in patients with HELLP syndrome may avoid additional surgery in patients that go on to develop DIC.
严重HELLP综合征合并多器官损害和DIC:引流管放置的作用:1例报告
背景:弥散性血管内凝血(DIC)可出现在溶血、肝酶升高、低血小板(HELLP)综合征的妇女产后。本报告强调了紧急剖宫产术后引流管插入的重要性。这将避免开腹探查手术的需要。案例:在妊娠34周时,一名P1G4妇女被诊断患有严重的先兆子痫和HELLP综合征,她的婴儿患有宫内生长受限(IUGR)和胎儿窘迫。这名妇女接受了肼、拉贝他洛尔、甲基多巴、硫酸镁治疗,并进行了紧急剖宫产手术。几小时后,该妇女出现DIC。给予红细胞(RBC),新鲜冷冻血浆(FFP)和血小板(PLTs),并进行腹部CT检查,发现腹内和前直肌鞘血肿。开腹探查术确定出血区域,并插入引流管监测出血情况。患者接受密切监测,血流动力学恢复稳定。结论:DIC是HELLP综合征女性常见的产后并发症。这些妇女在剖宫产术后先发制人的引流管插入可以避免发生DIC时需要额外的翻修手术。目前缺乏关于这一主题的明确指导方针。教学要点:对于诊断为HELLP综合征的妇女,如果后来发展为DIC,术后放置引流管可以避免额外的手术。对HELLP综合征患者在剖宫产后预先放置手术引流管可以避免继续发展为DIC的患者进行额外的手术。
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