{"title":"非小細胞肺癌切除後において再発時に肝転移巣のみを認めた症例の検討","authors":"Ryo Tanaka, Ryu Kanzaki, Hirokazu Watari, Sachi Kawagishi, Akiisa Omura, Tomohiro Maniwa, Jiro Okami","doi":"10.2995/jacsurg.37.502","DOIUrl":null,"url":null,"abstract":"非小細胞肺癌術後再発時に肝転移のみを認めた11例の検討を行った.男/女:9/2例,手術時年齢中央値73(45-78)歳,術式は葉/区切:10/1例.組織型は腺癌(Ad)/扁平上皮癌(Sq)/他:6/4/1例.肺切除から肝転移再発までの期間は,中央値7(3-12)ヵ月.再発時治療は,肝切除1例,化学療法10例.肝転移再発後全例で進行を認め,再発治療後のPFS中央値は5(1-23)ヵ月,OS中央値は21(8-47)ヵ月であった.肝転移後経過中4例(内Sq3例)で肝以外に再発を認めず,7例(Ad/Sq:6/1例)で肝以外の再発を認め,肝以外に再発を認めない症例はSqが多い傾向であった.全例で肝転移と脳転移の病勢制御が困難で,最終転帰は担癌生存4例,原病死7例であった.本検討と文献的考察を合わせ,肺癌術後肝転移再発に対してはSqが局所治療の適応と考えられるが,今後更なる症例集積が望ましい.","PeriodicalId":498875,"journal":{"name":"The Journal of The Japanese Association for Chest Surgery","volume":"133 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of The Japanese Association for Chest Surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2995/jacsurg.37.502","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}