[The interaction of cytostatic compounds with urinary enzymes. 1. The influence on acylase from the human kidney].

Zeitschrift fur medizinische Laboratoriumsdiagnostik Pub Date : 1990-01-01

H J Hütter, R Pantschewa-Haschen

引用次数: 0

Abstract

Acylase, a cytosolic carboxypeptidase of human kidneys, is inhibited by various xenobiotics as well as by the physiological pH of human urine in the range of pH 4.5-5.8. Caused by this, the enzyme is unsuited for the demonstration of nephrotoxic processes.

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细胞抑制化合物与尿酶的相互作用。1. 对人肾酰基化酶的影响[j]。

酰基酶是人体肾脏的一种胞质羧肽酶，多种外源性药物及人体尿液pH值在4.5-5.8范围内均可抑制酰基酶的活性。因此，该酶不适合用于肾毒性过程的演示。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Zeitschrift fur medizinische Laboratoriumsdiagnostik

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