Study of Electrocardiographic Changes and Spirometry Findings in Chronic Obstructive Lung Disease

JNGMC Pub Date : 2023-09-01 DOI:10.3126/jngmc.v21i1.58298
Tilchan Pandey, Jeevan Khanal, Resham Gautam, Shami Pokhrel
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Abstract

Introduction: Chronic Obstructive Pulmonary Disease is one of the top three causes of death worldwide and patients have to do pulmonary function test by spirometry to diagnose and to evaluate the severity. Electrocardiogram abnormalities have been found uniformly increasing with the severity by Global Initiative for Obstructive Lung Disease stages. Aims: To know the role of Electrocardiogram in the evaluation of severity of Chronic Obstructive Lung Disease. Methods: This was conducted in the department of Internal Medicine of Lumbini Medical College Teaching hospital from December 2021 to June 2022. The Chronic Obstructive Pulmonary Lung Disease was established with history, examination and spirometry along with Electrocardiogram. Results: Among 72 patients included 40 (55.56%) were in mild to moderate stage and 32 (44.44%) were in severe stage. The mean Force Expiratory Volume in one Second/Force Vital Capacity of severe stage was 38.59± 6.9 and 66.32±7.37 in mild to moderate stages. The electrocardiographic abnormalities like right atrial enlargement (P –pulmonale), right ventricular hypertrophy, complete right bundle branch block, low voltage in limbs, right axis deviation, sinus tachycardia and supraventricular tachycardia were seen in severe stage with statistical significance (p<0.05). Whereas left axis deviation and premature atrial contraction were found in mild to moderate disease and was statistically not significant.Increased percentage of normal electrocardiogram was found in mild or moderate than severe stage with statistical significance. So it is inversely related with the severity of disease. Conclusion: The relationship between Electrocardiogram findings and degree of airway obstruction was found to be highly significant. So, Electrocardiogram can be used as a surrogate investigation to evaluate the severity of Chronic Obstructive Pulmonary Disease.
慢性阻塞性肺疾病的心电图变化和肺活量测定研究
慢性阻塞性肺疾病是全球三大死亡原因之一,患者必须通过肺活量测定法进行肺功能检查来诊断和评估其严重程度。根据全球阻塞性肺疾病分级,心电图异常随着严重程度的增加而一致增加。 目的:了解心电图在慢性阻塞性肺疾病严重程度评价中的作用。 方法:研究于2021年12月至2022年6月在蓝毗尼医学院附属医院内科进行。通过病史、检查、肺活量测定及心电图确定慢性阻塞性肺疾病。结果:72例患者中轻中度40例(55.56%),重度32例(44.44%)。重度患者平均1秒用力呼气量/用力肺活量为38.59±6.9,轻、中度患者平均为66.32±7.37。严重度出现右房增大(P -pulmonale)、右心室肥厚、右束支完全阻滞、四肢低电压、右轴偏曲、窦性心动过速、室上性心动过速等心电图异常,差异均有统计学意义(P < 0.05)。而左心轴偏曲和心房早缩在轻中度疾病中存在,且无统计学意义。轻、中度期心电图正常率高于重度期,差异有统计学意义。因此,它与疾病的严重程度成反比。 结论:心电图表现与气道梗阻程度有高度相关性。因此,心电图可以作为评估慢性阻塞性肺疾病严重程度的替代调查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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