Intensity Modulated Radiotherapy For Recurrent Spine Aneurysmal Bone Cyst In Adolescence-Case Report And Review of Literature

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Abstract

Aneurysmal bone cysts are rarely diagnosed aggressive benign bone tumors that require CT and MRI imaging and strict histopathological analysis. This clinically and histologically benign tumor is mainly diagnosed in children and adolescents in the long bones of the limbs, but in 12%-30% it is localized in the spine. Since the value of external beam radiotherapy (EBRT) for aneurysmal bone cyst (ABC) has not been well defined, we present our observations and treatment outcome after the realization of intensity modulated radiotherapy (IMRT) up to total dose 30 Gy for recurrent spine aneurysmal bone cyst in adolescent age. In this article, for the first time in the world medical literature, an MRI imaging finding after performed IMRT in recurrent ABC is presented. Our observations lead to the conclusion, that radiation therapy is an effective treatment method for relapsed or inoperable disease, achieving not only a symptomatic pain-relieving effect, but also a significant tumor reduction and restoration of the bone structure.
调强放疗治疗青少年复发性脊柱动脉瘤性骨囊肿1例报告及文献复习
动脉瘤性骨囊肿很少被诊断为侵袭性良性骨肿瘤,需要CT和MRI成像和严格的组织病理学分析。这种临床和组织学上的良性肿瘤主要诊断于儿童和青少年的四肢长骨,但有12%-30%的肿瘤局限于脊柱。由于外束放疗(EBRT)治疗动脉瘤性骨囊肿(ABC)的价值尚未明确,我们介绍了在实现总剂量为30 Gy的调强放疗(IMRT)治疗青少年复发性脊柱动脉瘤性骨囊肿后的观察和治疗结果。在这篇文章中,在世界医学文献中首次提出了复发性ABC行IMRT后的MRI成像发现。我们的观察得出结论,放射治疗是复发或不能手术的疾病的有效治疗方法,不仅可以缓解症状性疼痛,而且可以显著缩小肿瘤和恢复骨结构。
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