[Study of the effect of vinblastine on hair growth in rats].

IF 0.5 Q4 DERMATOLOGY

Przeglad dermatologiczny Pub Date : 1990-01-01

L Brzezińska-Wcisło

引用次数: 0

Abstract

In the trichological studies on the model of Wistar rats aged 4-5 weeks intraperitoneal vinblastine in doses of 0.008-0.030 mg/100 g of body weight caused initially mixed (dystrophic-telogenic) hair loss. After higher doses and longer drug administration the mechanism of hair loss was transformed to dystrophic. In both forms of hair loss signs of advanced diffuse alopecia were found.

本刊更多论文

长春碱对大鼠毛发生长影响的研究

在4-5周龄Wistar大鼠模型的毛发学研究中，以0.008-0.030 mg/100 g体重的剂量腹腔注射长春花碱可引起初期混合性(营养不良-止发性)脱发。在高剂量和长时间给药后，脱发的机制转变为营养不良。在这两种形式的脱发中都发现了晚期弥漫性脱发的迹象。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Przeglad dermatologiczny DERMATOLOGY-

CiteScore

0.80

自引率

14.30%

发文量

审稿时长

12 weeks

期刊介绍： Przegląd Dermatologiczny (ang. Dermatological Review) is a bimonthly magazine of the Polish Dermatological Association. It publishes original (clinical and experimental) papers, review papers, care reports, reports from congresses, reviews of books, announcements, letters to the editor and special papers (requested by the editors), concerning selected dermatological and interdisciplinary issues. Papers sent to the editor are reviewed.