[Necrobiosis lipoidica].

Abstract

Authors report results of light and electron microscopic studies of dermal symptoms of 8 patients with non-diabetic lipoid necrobiosis. In all cases microangiopathy in skin, characterized by thickening of basal lamina and its becoming multilayered, and by narrowing of lumen of veins. Histological picture of dermal symptoms showed tuberculoid structure, which is characteristic of symptoms of non-diabetic necrobiosis. Orgastoplasmatic corpuscles found in plasma cells are conditioned upon atypical immune globulin synthesis.