Relationship Between Severity of Multiple Sclerosis and Fear of Falling Mediated by Cognitive and Physical Factors

Atena Kohestani, Seyedeh Zahra Sadati, Shahnam Abolghasemi
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Abstract

Background & Aims: Multiple sclerosis (MS) patients are exposed to various health threats, including fear of falling (FOF), which restricts their daily life activities and cause isolationism and lower social participation. The present study aimed to investigate the relationship between the severity of MS and FOF through the mediating role of cognitive and physical factors in patients with MS. Materials and Methods: This was a correlational study based on path analysis. The statistical population consisted of all patients with MS who visited the neurology centers of hospitals in Sari, Iran, 200 of whom were selected as the sample using convenience sampling. The research instruments included the Falls Efficacy Scale-International (FES-I), MS Severity Scale, Cognitive Factors Questionnaire, and the MOS 36-item Short-Form Health Survey (SF-36). Results: The results indicated that there was a negative and significant relationship between FOF and cognitive and physical factors and also a positive and significant relationship between FOF and the severity of MS (P<0.01). In addition, the results corroborated the negative and significant relationship between the severity of MS and physical factors (P<0.01). However, the direct relationship between the severity of MS and cognitive factors were excluded from the model because it was not established. The study findings confirmed the relationship between FOF and the severity of MS mediated by cognitive and physical factors (P<0.001). Conclusion: According to the results FOF was found to be much higher among patients with higher MS severity. The severity of MS had a positive relationship with FOF in the patients. Moreover, cognitive and physical factors had a mediating role in the relationship between the severity of MS and FOF.
认知和生理因素介导的多发性硬化严重程度与跌倒恐惧的关系
背景,目的:多发性硬化症(MS)患者面临各种健康威胁,包括害怕跌倒(FOF),这限制了他们的日常生活活动,导致孤立主义和社会参与度降低。本研究旨在通过认知和生理因素在多发性硬化症患者中的中介作用,探讨多发性硬化症严重程度与FOF之间的关系。统计人群为在伊朗Sari市医院神经病学中心就诊的所有MS患者,采用方便抽样法选取200人作为样本。研究工具包括国际瀑布疗效量表(FES-I)、多发性硬化症严重程度量表、认知因素问卷和MOS 36项简短健康调查(SF-36)。结果:FOF与认知、生理因素呈显著负相关,与MS严重程度呈显著正相关(P<0.01)。此外,结果证实MS的严重程度与物理因素呈负相关且显著(P<0.01)。然而,由于模型尚未建立,MS的严重程度与认知因素之间的直接关系被排除在模型之外。研究结果证实了FOF与MS严重程度之间存在认知和生理因素介导的关系(P<0.001)。结论:MS严重程度越高,FOF发生率越高。MS的严重程度与患者的FOF呈正相关。此外,认知和生理因素在MS严重程度与FOF的关系中起中介作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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