Evaluation the effect of use of different levels of mallow (Malva Sylvestris) derived extracts on cutaneous skin lesions healing in Simmental heifers

Abstract

To determine the effect of different levels of mallow derived extracts on Simmental heifer’s cutaneous skin lesions by second intention, forty Simmental heifers by average age, 16 months and average weight of 270±45 kg (mean+SD) were selected to evaluate cutaneous lesions healing after treatment with different levels of mallow derived extracts. Experimental wound excision model in Simmental heifers was created by means of a skin punch of 2 cm diameter. The heifers were topically treated for 18 days with a saline control or decoctions of mixed with common thistle and thyme derived extracts with carboxymethyl cellulose. The centripetal retraction, clinical, and histological aspects of the wounds were observed until complete healing. The phototherapeutics agent presents in thyme improved cicatrization of cutaneous lesions in cattle skin during the first days of treatment. The treatments were beneficial to the reparation process. The phytotherapeutics agent present in mallow derived extracts showed positive effects in the inflammatory phase and on the reparation process. The mallow derived extracts at 200 mg showed a positive effect on the macroscopic aspect of cutaneous lesions in heifers only during the first treatment days. In conclusion different levels of mallow derived extracts improved fibroplasia and its pytotherapeutic activity may be useful in topical treatment of cutaneous lesions in Simmental heifers