Information Technology for Multiparametric Analysis of Laser Images of Biological Fluid Films in Biomedical Applications

Yuriy Ushenko, Ivan Gordey, Yuriy Tomka, Irina Soltys, Oksana Bakun, Zhengbing Hu
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Abstract

At the current moment, all developed polarization methods utilize "single-point" statistical analysis algorithms for laser fields. A relevant task is to generalize traditional techniques by incorporating new correlation-based "two-point" algorithms for the analysis of polarization images. Theoretical foundations of the mutual and autocorrelation processing of phase maps of polarization-structural images of samples of dehydrated serum films are given. The maps of a new polarization-correlation parameters, namely complex degree of coherence (CDC) and complex degree of mutual polarization (CDMP) of soft matter layer boundary field by the example of dehydrated serum film samples are investigated. Two groups of representative samples, uterine myoma patients (control group 1) and patients with external genital endometriosis (study group 2), were considered. We applied a complex algorithm of analytical data processing - statistical (1stand 4th central statistical moments), correlation (Gram-Charlie expansion coefficients of autocorrelation functions) and fractal (fractal dimensions) parameters of polarization-correlation parameters maps. Objective markers for diagnosing extragenital endometriosis were found.
生物医学应用中生物流体膜激光图像多参数分析的信息技术
目前,所有已开发的偏振方法都使用激光场的“单点”统计分析算法。一个相关的任务是通过结合新的基于相关的“两点”算法来推广传统技术,以分析偏振图像。给出了脱水血清膜样品偏振结构图像相图相互和自相关处理的理论基础。以脱水血清膜样品为例,研究了软物质层边界场的复合相干度(CDC)和复互极化度(CDMP)这两个新的极化相关参数的映射。我们将子宫肌瘤患者(对照组1)和外生殖器子宫内膜异位症患者(研究组2)作为两组代表性样本。我们采用了一种复杂的分析数据处理算法——统计(1 - 4中心统计矩)、相关(自相关函数的Gram-Charlie展开系数)和分形(分形维数)参数的极化相关参数图。目的寻找诊断子宫外子宫内膜异位症的标志物。
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