Retrospective study of 69 cases of cerebral cystic echinococcosis in patients admitted to National hospital in Bishkek city, Kyrgyzstan

Abstract

Introduction and Aim: Cystic echinococcosis (CE) is a severe, widespread parasitic sickness that continues to be a significant health concern in many countries. The goal of the study was to find out how well ozonized saline solution (O3SS) cleans hydatid cysts to improve the results of neurosurgical treatment for patients with cerebral CE and to make suggestions for preventing the disease. Methods: This study included 69 patients with cerebral CE who were operated in our hospital. The diagnosis was confirmed at the time of the surgery, which allowed us to evaluate the data of computerized tomography in 22 (31.9%) and magnetic resonance imaging in 47 (68.1%) patients of the brain. Results: All 69 examined patients presented with cysts of parasitic origin, which were confirmed intraoperatively. Intact removal of hydatid cysts using the Dowling-Orlando technique was performed in 43 cases (62.3%). The best exposure duration for processing residual cavities in brain echinococcosis utilizing O3SS is 10 minutes. The duration of the follow-up period ranged from 8–18 months. Conclusion: When larvocysts of CE are exposed to 10–15 mg/l of O3SS, the germ cells go through irreversible changes in their ultrastructure that stop them from making new cysts within five minutes.