Effect of haematocrit on wound healing in children.

Zeitschrift fur Kinderchirurgie : organ der Deutschen, der Schweizerischen und der Osterreichischen Gesellschaft fur Kinderchirurgie = Surgery in infancy and childhood Pub Date : 1990-06-01 DOI:10.1055/s-2008-1042569

J Viljanto

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引用次数: 2

Abstract

The effects of mild or moderate normovolaemic anaemia on wound healing (WH) continue to be debatable. The results of animal experiments and clinical experience are somewhat controversial. In this study, sixty-six boys, aged from 5 to 15, mean 10.1 years, were routinely operated on for a unilateral inguinal hernia, after which their WH was studied by the Cellstic device. Based on differential count of wound cells and their mutual transformed cell to cell ratios it was found that the optimum level of haematocrit (Hct) for WH was 37-39% with haemoglobin (Hb) values of 12.0-12.4 g/100 ml. Hct values under and over these limits began to retard WH significantly (p less than 0.02) without any visual signs of delay in WH. Both values are below the age adjusted means but just above the lower limits of normal. It is thus allowed, for the majority of healthy children with normal blood values, a mild decrease of Hct during the operation without any harmful effect on WH.

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红细胞压积对儿童伤口愈合的影响。

轻度或中度等容性贫血对伤口愈合(WH)的影响仍有争议。动物实验结果和临床经验存在一定的争议。在这项研究中，66名年龄在5到15岁之间的男孩，平均10.1岁，接受了单侧腹股沟疝的常规手术，之后用Cellstic装置研究了他们的WH。根据伤口细胞的差异计数和它们相互转化的细胞与细胞的比率，发现肝纤维化的最佳红细胞压积(Hct)水平为37-39%，血红蛋白(Hb)值为12.0-12.4 g/100 ml。低于和超过这些限值的Hct开始显著延缓肝纤维化(p小于0.02)，而没有肝纤维化延迟的任何视觉迹象。这两个值都低于年龄调整后的平均值，但略高于正常值的下限。因此，对于大多数血值正常的健康儿童，允许在手术期间Hct轻度下降，而对WH没有任何有害影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Zeitschrift fur Kinderchirurgie : organ der Deutschen, der Schweizerischen und der Osterreichischen Gesellschaft fur Kinderchirurgie = Surgery in infancy and childhood

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