Laparoscopic sleeve gastrectomy vs laparoscopic single anastemosis sleeve ileal bypass in control of triglyceridemia in obese patients

Ahmed Raafat Saad Abdeen, Samir Ahmed Abd El Majeed, Abd El Rahman M Galal
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Abstract

Background: An independent risk factor for atherosclerotic heart disease is hypertriglyceridemia (HTG). Acute pancreatitis is also a danger for people with serum triglyceride (TG) levels >1000 mg/dL. The most successful weight loss treatment now available has been proven to be bariatric surgery. The aim of this work was to compare between laparoscopic sleeve gastrectomy (LSG) versus laparoscopic Single anastomosis Sleeve Ileal bypass in control of HTG in obese patients.Methods: Fifty-two individuals, aged 18 to 65, of both sexes, with a BMI of 30 to 55 kg/m2, T2D, a history of prior unsuccessful weight loss attempts, and strong surgical motivation were included in this prospective study. Type 1 diabetics, those above the age of 15, people with BMIs under 30, people over 55, those who had previously undergone gastric or obesity surgery, and women who were pregnant were all excluded from the study. The included patients were split into two groups: obese patients in group I (N=26) had LSG, while obese patients in group II (N=26) got laparoscopic gastric bypass.Results: The mean cholesterol after 3 months was 156.92±14.90 and 163.08±16.31 between bypass and LSG respectively. There was no statistically significant difference between the bypass and LSG. The cholesterol level after 3 months all participants were desirable in bypass, was 96.15% desirable in LSG and 3.85% non-desirable bypass in LSG. The mean triglyceride after 3 months was 129.23±13.47 and 144.62±14.21 between bypass and LSG respectively. There was a statistically significant difference between the bypass and LSG. Triglyceride level after 3 months was desirable in 92.31% bypass and 57.69% LSG and nor desirable in 7.69% bypass and 42.31% LSG between bypass and LSG. There was a statistically significant difference between the bypass and LSG.Conclusions: Gastric bypass was associated produce more favorable outcomes compared LSG in diabetes obese patients. This is observed in more weight loss after 1-year, better lipid profile after 3 months.
腹腔镜袖式胃切除术与腹腔镜单口吻合袖式回肠旁路术控制肥胖患者甘油三酯血症的比较
背景:动脉粥样硬化性心脏病的一个独立危险因素是高甘油三酯血症(HTG)。血清甘油三酯(TG)水平>1000 mg/dL的人也有急性胰腺炎的危险。目前最成功的减肥方法是减肥手术。本研究的目的是比较腹腔镜袖式胃切除术(LSG)与腹腔镜单吻合术袖式回肠旁路术在控制肥胖患者HTG方面的效果。方法:本前瞻性研究纳入了52名年龄在18 - 65岁的男性和女性,BMI在30 - 55 kg/m2之间,T2D,既往有减肥失败史,手术动机强。1型糖尿病患者、15岁以上的人、bmi低于30的人、55岁以上的人、以前做过胃部或肥胖手术的人以及怀孕的妇女都被排除在研究之外。纳入的患者分为两组:I组肥胖患者(N=26)行LSG, II组肥胖患者(N=26)行腹腔镜胃旁路术。结果:3个月后,两组患者的平均胆固醇分别为156.92±14.90和163.08±16.31。旁路与LSG之间无统计学差异。3个月后,所有参与者的胆固醇水平均达到理想水平,其中LSG组为96.15%,LSG组为3.85%。旁路组和LSG组3个月后的平均甘油三酯分别为129.23±13.47和144.62±14.21。旁路和LSG之间的差异有统计学意义。3个月后的甘油三酯水平在92.31%的旁路组和57.69%的LSG组是理想的,而在7.69%的旁路组和42.31%的LSG组之间不理想。旁路和LSG之间的差异有统计学意义。结论:与LSG相比,胃旁路治疗糖尿病肥胖患者可产生更有利的结果。这在1年后体重减轻更多,3个月后血脂水平更好。
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