New comprehensive method for treatment of atrophic skin scars

S. Yu. Dolgikh, A. G. Stenko, N. V. Gryazeva
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Abstract

Striae distensae, commonly known as stretch marks, are visible linear atrophic scars. Despite quite numerous studies, the lack of a unified approachto the problem of treating atrophic scars, a detailed clinical and morphological classification leads to the fact that doctors empirically choosepatient management tactics, which leads to unreliability or even lack of effect, the need for numerous repeated courses of therapy, and significanteconomic costs. The article presents data on studying the effectiveness of various methods of therapy. Depending on the method of therapy,patients were divided into three groups by simple randomization. The study used a visual analogue scale (VAS) to assess the clinical symptomsof AR. The combined use of fractional ablative laser and PDT with the topical photosensitizer chlorin e6 is highly effective in the treatment ofatrophic scars lasting more than a year (VAS dynamics – 74.9 %), fractional ablative laser is moderately effective in long-term atrophic scars (VASdynamics – 65.6 %), while PDT in the form of monotherapy is insufficiently effective (VAS dynamics – 45.6 %).
萎缩性皮肤疤痕综合治疗新方法
扩张纹,俗称妊娠纹,是可见的线状萎缩性疤痕。尽管有大量的研究,但对于治疗萎缩性疤痕的问题缺乏统一的方法,详细的临床和形态学分类导致医生根据经验选择患者管理策略,这导致不可靠甚至缺乏效果,需要多次重复治疗,并且经济成本高。本文介绍了研究各种治疗方法有效性的数据。根据治疗方法的不同,采用简单随机法将患者分为三组。本研究采用视觉模拟量表(VAS)评估AR的临床症状,分次烧蚀激光和PDT联合使用局部光敏剂氯e6对持续一年以上的萎缩性疤痕非常有效(VAS动力学- 74.9%),分次烧蚀激光对长期萎缩性疤痕中等有效(VAS动力学- 65.6%),而PDT单药治疗效果不足(VAS动力学- 45.6%)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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