Effects of Participating in Religious Groups on Mental Health Issues: A Two-Sample Mendelian Randomization Study

IF 1.7 2区哲学 Q2 PSYCHOLOGY, MULTIDISCIPLINARY

International Journal for the Psychology of Religion Pub Date : 2023-10-09 DOI:10.1080/10508619.2023.2267956

Hansen Li, Xing Zhang, Yang Cao, Guodong Zhang

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引用次数: 0

Abstract

ABSTRACTWe conducted a Mendelian randomization study to evaluate the potential causal effects of attending religious groups on the prevalence of depression, generalized anxiety disorders, anxiety disorders, and suicide and self-harm. Data from the UK Biobank and the FinnGen project were processed by inverse variance weighting (IVW), weighted median, and MR-Egger regression methods. Despite certain pleiotropic risks, we found that attending religious groups was potentially associated with a reduced risk of anxiety disorders (OR = 0.213, p = .028). The pleiotropies were largely controlled and the effect on anxiety disorders became more significant in our sensitivity analysis (OR = 0.162; p = .006). Additionally, attending religious groups was associated with a reduced risk of suicide and self-harm (OR = 0.231, p = .0006). However, we did not observe any substantial protection against depression. In conclusion, our study adds to the existing literature and sheds light on the potential health benefits of religious activities from a novel perspective. Disclosure statementNo potential conflict of interest was reported by the author(s).Data availability statementThe data that support the findings of this study are openly available in IEU Open GWAS project at https://gwas.mrcieu.ac.uk/, reference code: ukb-b-4667; finn-b-F5_DEPRESSIO; finn-b-F5_GAD; finn-b-KRA_PSY_ANXIETY; and finn-b-VWXY20_SUICI_OTHER_INTENTI_SELF_H.

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参与宗教团体对心理健康问题的影响:一项双样本孟德尔随机研究

摘要本研究采用孟德尔随机化研究，评估参加宗教团体对抑郁症、广泛性焦虑障碍、焦虑障碍、自杀和自残患病率的潜在因果影响。来自UK Biobank和FinnGen项目的数据采用逆方差加权(IVW)、加权中位数和MR-Egger回归方法进行处理。尽管存在一定的多效性风险，但我们发现参加宗教团体与降低焦虑障碍风险存在潜在关联(OR = 0.213, p = 0.028)。在我们的敏感性分析中，多效性在很大程度上得到了控制，对焦虑障碍的影响变得更加显著(OR = 0.162;P = .006)。此外，参加宗教团体与降低自杀和自残风险相关(OR = 0.231, p = 0.0006)。然而，我们没有观察到对抑郁症有任何实质性的保护。总之，我们的研究补充了现有的文献，并从一个新的角度阐明了宗教活动对健康的潜在益处。披露声明作者未报告潜在的利益冲突。数据可用性声明支持本研究结果的数据可在IEU Open GWAS项目中公开获取https://gwas.mrcieu.ac.uk/，参考代码:ukb-b-4667;finn-b-F5_DEPRESSIO;finn-b-F5_GAD;finn-b-KRA_PSY_ANXIETY;和finn-b-VWXY20_SUICI_OTHER_INTENTI_SELF_H。

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来源期刊

International Journal for the Psychology of Religion Multiple-

CiteScore

4.20

自引率

4.50%

发文量

期刊介绍： The International Journal for the Psychology of Religion (IJPR) is devoted to psychological studies of religious processes and phenomena in all religious traditions. This journal provides a means for sustained discussion of psychologically relevant issues that can be examined empirically and concern religion in the most general sense. It presents articles covering a variety of important topics, such as the social psychology of religion, religious development, conversion, religious experience, religion and social attitudes and behavior, religion and mental health, and psychoanalytic and other theoretical interpretations of religion. The journal publishes research reports, brief research reports, commentaries on relevant topical issues, book reviews, and statements addressing articles published in previous issues. The journal may also include a major essay and commentaries, perspective papers of the theory, and articles on the psychology of religion in a specific country.