Biodiversity and Biopharmaceuticals of Endophytic Fungi Associated with Medicinal Plants Therapeutic Activity: Case studies of Lamiaceae Crops

Abstract

Endophytes present a potential for the exploitation of many secondary metabolites. This paper dis¬cusses the biodiversity of endophytes and their biopharmaceutical prospects in the members of Lamiaceae. Several genera of fungal endophytes were predominant in Lamiaceae plants including Diaporthe, Stem¬phylium, Botryosphaeria, Talaromyces, Fusarium, Cephalotheca, Cladosporium, Penicillium, Aspergillus, and Phoma can produce many types of secondary metabolites. Such secondary metabolites produced by the endophytes are involved in antioxidant, antidiabetic, antifungal, anticandidal, antileishmanial, anticancer, and anti-inflammatory activities, as well as mycopharmacological properties.