Manufacturing of Bioactive Biodegradable Scaffolds by Stereolithography

IF 1 Q3 ENGINEERING, MULTIDISCIPLINARY
Viktorya Rstakyan, Liana Mkhitaryan, Mikayel Torosyan, Zaruhi Karabekian, Gohar Sevoyan, Marina Aghayan, Miguel A. Rodríguez
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引用次数: 0

Abstract

In this study, we used Stereolithography to develop tricalcium phosphate-based scaffolds. The feedstock for the process consisted of a UV-curable resin, synthetic tricalcium phosphate, and silicon oxide. The viscosity and curability of the resins are carefully controlled to enable the fabrication of complex-shaped scaffolds. Following stereolithography, the ceramic-resin scaffolds were heat treated. The first step was debinding process followed by a sintering step. The resulting sintered samples underwent microstructure, chemical, and mechanical analysis to assess their properties. The optimized samples were then subjected to biodegradability and cytotoxicity tests to evaluate their suitability for use as tissue engineering scaffolds.
立体光刻技术制备生物活性生物可降解支架
在这项研究中,我们使用立体光刻技术来开发磷酸三钙基支架。该工艺的原料包括紫外光固化树脂、合成磷酸三钙和氧化硅。树脂的粘度和固化性被仔细控制,以使复杂形状支架的制造成为可能。在立体光刻之后,对陶瓷树脂支架进行热处理。第一步是脱脂,然后是烧结。所得到的烧结样品进行了微观结构、化学和力学分析,以评估其性能。然后对优化后的样品进行生物降解性和细胞毒性测试,以评估其作为组织工程支架的适用性。
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来源期刊
Advances in Science and Technology-Research Journal
Advances in Science and Technology-Research Journal ENGINEERING, MULTIDISCIPLINARY-
CiteScore
1.60
自引率
27.30%
发文量
152
审稿时长
8 weeks
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