The therapy for urogenital tuberculosis

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
Ekaterina KULCHAVENYA, Mete ÇEK
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 pre-antibiotic era: about 20% of patients in urological hospitals had renal TB, mostly in the form of pyonephrosis.
 We composed a narrative review of the literature with keywords “urogenital tuberculosis’, “prostate tuberculosis” “kidney tuberculosis”,
 “treatment of tuberculosis”.
 Urogenital TB (UGTB) includes TB of the kidney and the urinary tract and male and female genital TB. Each clinical presentation
 requires tailored antibiotic therapy depending on stage and general management. Anti-TB therapy should be multicomponent,
 continuous, long-lasting and controlled with a follow-up for 2-3 years. Otherwise, the risks of development of drug-resistance and
 relapse increase.
 Index of suspicion on UGTB is generally low, causing a delay in diagnosis; consequently, complicated forms of UGTB respond
 poorly to anti-TB therapy, while timely diagnosed “minor” forms are curable medically without surgery. Even with timely diagnosed
 UGTB, non-optimal therapy may result in over-fibrosis, scarring and strictures of the urinary tract, making surgical repair inevitable.
 Nevertheless, we have a wide enough spectrum of anti-TB drugs to cure urogenital TB.","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":"49 1","pages":"0"},"PeriodicalIF":0.2000,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Marmara Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5472/marumj.1368375","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0

Abstract

Tuberculosis (TB) is a communicable disease that is a major cause of ill health. Urogenital TB was a frequent urological disease in the pre-antibiotic era: about 20% of patients in urological hospitals had renal TB, mostly in the form of pyonephrosis. We composed a narrative review of the literature with keywords “urogenital tuberculosis’, “prostate tuberculosis” “kidney tuberculosis”, “treatment of tuberculosis”. Urogenital TB (UGTB) includes TB of the kidney and the urinary tract and male and female genital TB. Each clinical presentation requires tailored antibiotic therapy depending on stage and general management. Anti-TB therapy should be multicomponent, continuous, long-lasting and controlled with a follow-up for 2-3 years. Otherwise, the risks of development of drug-resistance and relapse increase. Index of suspicion on UGTB is generally low, causing a delay in diagnosis; consequently, complicated forms of UGTB respond poorly to anti-TB therapy, while timely diagnosed “minor” forms are curable medically without surgery. Even with timely diagnosed UGTB, non-optimal therapy may result in over-fibrosis, scarring and strictures of the urinary tract, making surgical repair inevitable. Nevertheless, we have a wide enough spectrum of anti-TB drugs to cure urogenital TB.
泌尿生殖系统结核的治疗
结核病(TB)是一种传染性疾病,是健康不良的主要原因。泌尿生殖系统结核是我国泌尿系统常见病;抗生素应用前:泌尿科医院约20%的患者患有肾性结核,多表现为脓肾。 我们以“泌尿生殖系统结核”、“前列腺结核”、“肾结核”、 “治疗肺结核” 泌尿生殖系统结核(UGTB)包括肾脏和泌尿系统结核以及男性和女性生殖系统结核。每个临床表现 需要根据病情和一般管理情况量身定制抗生素治疗。抗结核治疗应该是多组分的, 持续,持久,控制随访2-3年。否则,产生耐药性和 复发增加# x0D公司;UGTB的怀疑指数普遍较低,导致诊断延误;因此,复杂形式的UGTB响应 而及时诊断出的“轻微”形式在医学上无需手术即可治愈。即使诊断及时 UGTB,非最佳治疗可能导致尿路过度纤维化、瘢痕和狭窄,使手术修复成为必然。 然而,我们有足够广泛的抗结核药物来治疗泌尿生殖系统结核病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Marmara Medical Journal
Marmara Medical Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
0.30
自引率
0.00%
发文量
0
期刊介绍: Marmara Medical Journal, Marmara Üniversitesi Tıp Fakültesi tarafından yılda üç kere yayımlanan multidisipliner bir dergidir. Bu dergide tıbbın tüm alanlarına ait orijinal araştırma makaleleri, olgu sunumları ve derlemeler İngilizce veya Türkçe olarak yer alır.
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