Junior Barthelemy Mekeme Mekeme, Oriol Landry Mbouche, Figuim Bello, Bright Che Awondo, Aurele Achille Mbassi, Cedrick Jean Fouda, Tax Liendi, Marcella Biyouma, Guillaume Gayma, Marcel Junior Yon Mekeme, Junior Ngue Ngue,   Mabah, Paul Adrien Atangana, Pierre Ongolo Zogo, Pierre Joseph Fouda, Noel Coulibaly, Angwafo III Fru, Maurice Aurelien Sosso
{"title":"Comparison of Transrectal Prostate Digital and Ultrasound-Guided Core Biopsies in 400 Men in a Low-and-Middle Income Country","authors":"Junior Barthelemy Mekeme Mekeme, Oriol Landry Mbouche, Figuim Bello, Bright Che Awondo, Aurele Achille Mbassi, Cedrick Jean Fouda, Tax Liendi, Marcella Biyouma, Guillaume Gayma, Marcel Junior Yon Mekeme, Junior Ngue Ngue,   Mabah, Paul Adrien Atangana, Pierre Ongolo Zogo, Pierre Joseph Fouda, Noel Coulibaly, Angwafo III Fru, Maurice Aurelien Sosso","doi":"10.4236/oju.2023.1310048","DOIUrl":null,"url":null,"abstract":"Background: The diagnosis of prostate cancer (PCa) relies on clinical assessment with digital rectal examination, serum PSA and histological examination. Limitations in our technical facilities, high financial cost of ultrasound-guided biopsy often prevent us from implementing the guidelines on the practice of prostate biopsy. Methods: We conducted a retrospective and cross-sectional descriptive study comparing digital-guided and ultrasound-guided transrectal prostate biopsy of 400 patients over a period of 12 years in the Yaounde Central Hospital. We reviewed files of patients who underwent digital and ultrasound guided biopsy procedures. Data was analyzed using EPI info 7.0. Parametric variables were reported as means and standard deviations and percentages and counts were used to report categorical variables. Results: Out of the 400 patients, 292 digital-guided transrectal biopsies (73%) and 108 ultrasound-guided transrectal biopsies (27%) were performed in patients who were suspected of having prostate cancer (PCa). Patients were aged between 39 to 90 years. Both procedures were effective in identifying prostate cancer. Gleason score between 2 to 10 detected prostate adenocarcinoma for 301 patients (75.2%). The complications included anal pain, rectal bleeding, hematuria and urinary tract infections, with an occurrence rate similar for both ultrasound-guided (2.25%) and digitally-guided techniques (2.5%). Seven patients (1.75%) required hospitalization for management of complications. The mortality rate was null. Conclusion: Both techniques are effective in detecting PCa with the similar complication rates. Digital-guided trans-rectal prostate biopsy still has its place in a resource-limited setting like ours.","PeriodicalId":19545,"journal":{"name":"Open Journal of Urology","volume":"99 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Journal of Urology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4236/oju.2023.1310048","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background: The diagnosis of prostate cancer (PCa) relies on clinical assessment with digital rectal examination, serum PSA and histological examination. Limitations in our technical facilities, high financial cost of ultrasound-guided biopsy often prevent us from implementing the guidelines on the practice of prostate biopsy. Methods: We conducted a retrospective and cross-sectional descriptive study comparing digital-guided and ultrasound-guided transrectal prostate biopsy of 400 patients over a period of 12 years in the Yaounde Central Hospital. We reviewed files of patients who underwent digital and ultrasound guided biopsy procedures. Data was analyzed using EPI info 7.0. Parametric variables were reported as means and standard deviations and percentages and counts were used to report categorical variables. Results: Out of the 400 patients, 292 digital-guided transrectal biopsies (73%) and 108 ultrasound-guided transrectal biopsies (27%) were performed in patients who were suspected of having prostate cancer (PCa). Patients were aged between 39 to 90 years. Both procedures were effective in identifying prostate cancer. Gleason score between 2 to 10 detected prostate adenocarcinoma for 301 patients (75.2%). The complications included anal pain, rectal bleeding, hematuria and urinary tract infections, with an occurrence rate similar for both ultrasound-guided (2.25%) and digitally-guided techniques (2.5%). Seven patients (1.75%) required hospitalization for management of complications. The mortality rate was null. Conclusion: Both techniques are effective in detecting PCa with the similar complication rates. Digital-guided trans-rectal prostate biopsy still has its place in a resource-limited setting like ours.
背景:前列腺癌(PCa)的诊断依赖于直肠指检、血清PSA和组织学检查的临床评估。我们的技术设备的限制,超声引导活检的高财政成本经常阻碍我们实施前列腺活检的实践指南。方法:我们进行了一项回顾性和横断面描述性研究,比较了雅温得中心医院12年来400名患者的数字引导和超声引导下的经直肠前列腺活检。我们回顾了接受数字和超声引导活检手术的患者的档案。数据分析采用EPI info 7.0软件。参数变量用均值和标准差报告,分类变量用百分比和计数报告。结果:400例疑似前列腺癌(PCa)患者中,手指引导下行直肠活检292例(73%),超声引导下行直肠活检108例(27%)。患者年龄在39至90岁之间。这两种方法都能有效识别前列腺癌。Gleason评分在2 ~ 10分之间的301例(75.2%)患者检出前列腺癌。并发症包括肛门疼痛、直肠出血、血尿和尿路感染,超声引导和数字引导的发生率相似,分别为2.25%和2.5%。7例(1.75%)患者需要住院治疗并发症。死亡率为零。结论:两种方法检测前列腺癌均有效,并发症发生率相近。在像我们这样资源有限的地方,数字引导的经直肠前列腺活检仍然有它的一席之地。