Natalia S. Pavlova, Galina I. Pavlenko, Vasily I. Dorozhkin, Ekaterina S. Engasheva, Lyubov L. Zakharova
{"title":"STUDYING THE EFFECT OF FEED ADDITIVE «PHYTODOC NEURO» ON WHITE RATS IN A CHRONIC EXPERIMENT (message 2)","authors":"Natalia S. Pavlova, Galina I. Pavlenko, Vasily I. Dorozhkin, Ekaterina S. Engasheva, Lyubov L. Zakharova","doi":"10.36871/vet.san.hyg.ecol.202303016","DOIUrl":null,"url":null,"abstract":"Feed additives containing biologically active substances are increasingly used to neutralize the negative effects of various toxicants, stress, age-related changes in the brain and to improve the cognitive abilities of animals. The influence of the feed additive «Phytodoc neuro» in doses of 4; 12 and 20 g/kg of feed on the functional state of the liver, kidneys and nervous system, as well as the behavioral responses of white rats in a four-month experiment was studied. Upon receipt of the drug in a therapeutic dose, no negative changes were found on the part of organs and systems important for the body. On the contrary, in the fourth month of the experiment, there was a tendency to increase the body weight and capacity to work of the animals. The body weight of animals fed with the drug at doses of 12 and 20 g/kg, significantly increased at the end of the third month. At a dose of 12 g/kg, starting from the third, at a dose of 20 g/kg after the second and fourth months, muscle strength on the horizontal rod increased, which characterizes the saturation of the body with energy.","PeriodicalId":491484,"journal":{"name":"Проблемы ветеринарной санитарии, гигиены и экологии","volume":"40 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Проблемы ветеринарной санитарии, гигиены и экологии","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36871/vet.san.hyg.ecol.202303016","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Feed additives containing biologically active substances are increasingly used to neutralize the negative effects of various toxicants, stress, age-related changes in the brain and to improve the cognitive abilities of animals. The influence of the feed additive «Phytodoc neuro» in doses of 4; 12 and 20 g/kg of feed on the functional state of the liver, kidneys and nervous system, as well as the behavioral responses of white rats in a four-month experiment was studied. Upon receipt of the drug in a therapeutic dose, no negative changes were found on the part of organs and systems important for the body. On the contrary, in the fourth month of the experiment, there was a tendency to increase the body weight and capacity to work of the animals. The body weight of animals fed with the drug at doses of 12 and 20 g/kg, significantly increased at the end of the third month. At a dose of 12 g/kg, starting from the third, at a dose of 20 g/kg after the second and fourth months, muscle strength on the horizontal rod increased, which characterizes the saturation of the body with energy.