Efficacy of Herbal Medicine on Sleep Disorders in Parkinson’s Disease: A Review of Randomized Controlled Trials

The Journal of Internal Korean Medicine Pub Date : 2023-09-30 DOI:10.22246/jikm.2023.44.4.603

Ji-hyeon Kang, Kyungmin Baek

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Abstract

Objectives: This study reviewed randomized controlled trials (RCTs) investigating the efficacy of herbal medicine on sleep disorders associated with Parkinson’s disease and suggests a better research process.Methods: We searched for RCTs for herbal medicine treatments for sleep disorders related to Parkinson’s disease on July 31, 2023 using eight databases (PubMed, Embase, the Cochrane library, China National Knowledge Infrastructure [CNKI], the Research Information Service System [RISS], Science ON, the Oriental Medicine Advanced Searching Integrated System [OASIS], and the Korea Citation Index [KCI]). Cochrane’s risk of bias tool was used to assess the quality of the RCTs.Results: A total of 16 RCTs met all the inclusion criteria, and in most reports, the treatment group showed a significant improvement in sleep disorders compared to the control group. Total effective rate (TER), Pittsburgh Sleep Quality Index (PSQI), Unified Parkinson’s Disease Rating Scale (UPDRS), TCM Symptom Score (TSS), Parkinson’s Disease Sleep Scale (PDSS), etc., were used as evaluation indicators.Conclusion: Herbal medicine is a potential treatment for sleep disorders associated with Parkinson’s disease. However, the selected RCTs were of poor quality, and it is necessary to perform more systematic studies.

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草药治疗帕金森病睡眠障碍的疗效:随机对照试验综述

目的:本研究回顾了草药治疗帕金森病相关睡眠障碍的随机对照试验(rct)，并提出了更好的研究过程。方法:我们于2023年7月31日使用8个数据库(PubMed、Embase、Cochrane图书馆、中国知网(CNKI)、研究信息服务系统(RISS)、Science on、东方医学高级检索集成系统(OASIS)和韩国引文索引(KCI))检索与帕金森病相关的睡眠障碍的草药治疗的随机对照试验。采用Cochrane偏倚风险工具评估随机对照试验的质量。结果:共有16项rct符合所有纳入标准，在大多数报告中，治疗组与对照组相比，睡眠障碍有显著改善。采用总有效率(TER)、匹兹堡睡眠质量指数(PSQI)、统一帕金森病评定量表(UPDRS)、中医症状评分(TSS)、帕金森病睡眠量表(PDSS)等作为评价指标。结论:草药是帕金森病相关睡眠障碍的潜在治疗方法。然而，所选择的rct质量较差，有必要进行更系统的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Journal of Internal Korean Medicine

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