Therapeutic Effect of Magnesium Supplementation in Improving Quality of Life among Elderly Insomniac Participants

Q4 Medicine
Amna Liaqat, Bahisht Rizwan, Ayesha Amjad, Zunaira Rasool
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Abstract

Insomnia is increasing day by day, according to global prevalence it ranges from10%to40%with trouble falling asleep, remaining asleep, or having non-restorative sleep that is accompanied by daytime impairment or distress. Magnesium seems to play a key role in there gelation of sleep. Objective: To compare the therapeutic effect of magnesium supplementation in improving quality of life among elderly insomniac participants with control and treatment group. Methods: The study design was double blind randomized clinical trial. Purposive sampling technique was used to allocate gender elderly people. Data were collected from Al-Saida Shuhda old age home, Lahore and the participants were divided into two groups, 40 participants in each group. Group 0 (control group) were given regular diet without magnesium supplement for 8 weeks. Group 1 (treatment group were given Magnesium supplements (500mg) for 8 weeks. Data were tabulated and analyzed with the help of SPSS 25.0. Results: The results shown that the magnesium supplementation had highly significant results in improving LSEQ, serum magnesium, serum melatonin, serum cortisol and serum renin level without showing any side effects. Group 0 has shown 0.152 (GTS), 0.088(QOS), 0.168(AFS), 0.195(BFW), 0.292(serum Mg), 0.567(serum melatonin), 0.276(serum cortisol), 0.101(serum renin) whereas group 1 has shown 0.01(GTS), 0.01(QOS), 0.003(AFS) and 0.03(BFW), 0.02(serum Mg), 0.01(serum melatonin), 0.02(serum cortisol), 0.02(serum renin), respectively. Conclusions: It was concluded from the results that magnesium supplementation in elderly people has highly significant effects in improving insomnia and quality of sleep.
补充镁对改善老年失眠症患者生活质量的治疗效果
失眠症日益增多,根据全球患病率,失眠症发生率在10%至40%之间,伴有入睡困难、保持睡眠状态或伴有白天障碍或痛苦的非恢复性睡眠。镁似乎在睡眠凝胶中起着关键作用。目的:比较补镁对老年失眠症患者生活质量的改善作用与对照组和治疗组的差异。方法:采用双盲随机临床试验。采用目的抽样方法对性别老年人进行分配。数据从拉合尔的Al-Saida Shuhda养老院收集,参与者分为两组,每组40名参与者。0组(对照组)给予正常饮食,不添加镁,持续8周。组1(治疗组)给予镁补充剂(500mg),连续8周。用SPSS 25.0软件对数据进行统计和分析。结果:结果显示,补镁对改善LSEQ、血清镁、血清褪黑素、血清皮质醇和血清肾素水平均有极显著效果,且无副作用。0组分别为0.152 (GTS)、0.088(QOS)、0.168(AFS)、0.195(BFW)、0.292(血清Mg)、0.567(血清褪黑素)、0.276(血清皮质醇)、0.101(血清肾素);1组分别为0.01(GTS)、0.01(QOS)、0.003(AFS)、0.03(BFW)、0.02(血清Mg)、0.01(血清褪黑素)、0.02(血清皮质醇)、0.02(血清肾素)。结论:老年人补充镁对改善失眠和睡眠质量有非常显著的作用。
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来源期刊
Pakistan Journal of Medical & Health Sciences
Pakistan Journal of Medical & Health Sciences MEDICINE, GENERAL & INTERNAL-
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期刊介绍: Pakistan Journal of Medical and Health Sciences is an international biomedical journal from Pakistan. We publish materials of interest to the practitioners and scientists in the broad field of medicine. Articles describing original qualitative, quantitative, human/animal clinical or laboratory studies are considered for publication.
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