A Review on Thrombolysis Enhancing Indian Edible Plants

Q3 Pharmacology, Toxicology and Pharmaceutics

Biomedical and Pharmacology Journal Pub Date : 2023-09-30 DOI:10.13005/bpj/2709

Vartika Jain, Bhavika Kunwar, S. K. Verma

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Abstract

Impaired thrombolysis is one of the causes of the development of cardiovascular diseases (CVD). The synthetic thrombolytic agents such as streptokinase, urokinase and antistreplase have their own side effects. Plants are always considered as safe and cost-effective therapeutic agents. Dietary therapeutics is an emerging branch for the prevention and treatment of several ailments. The present article compiles 43 edible plants which have shown in vitro thrombolytic potential and are also employed in the diets of several ethnic communities in India. Among these, Bauhinia purpurea and Baccaurea ramiflora are two plants having more than 70% in vitro clot lysis potential; Coccinia grandis, Curcuma longa, Cyperus rotundus, and Typha domingensis have 50-70% thrombolytic activity; and the rest of the plants have 11-49% thrombolytic activity. These 43 plants also include spices and condiments such as Turmeric, Black pepper, Indian Bayleaf, Coriander and Ginger, which affirms the traditional saying of using food as medicine. Besides, these edible plants also possess various phyto-constituents and health-beneficial pharmacological activities. If these plants could be incorporated into a routine diet, it might be possible to prevent or delay the onset of CVD. However, detailed studies are required to evaluate the pattern of CVD in ethnic communities consuming such plants, as well as systematic clinical trials are warranted to investigate the thrombolytic efficacy of these plants.

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促进印度食用植物溶栓的研究进展

血栓溶解障碍是导致心血管疾病(CVD)发生的原因之一。人工合成的溶栓药物如链激酶、尿激酶和抗链激酶都有其自身的副作用。植物一直被认为是安全、经济的治疗药物。饮食疗法是预防和治疗几种疾病的一个新兴分支。本文汇编了43种可食用植物，这些植物已显示出体外溶栓潜力，也被用于印度几个民族社区的饮食中。其中紫荆和巴卡杜鹃是体外溶血电位超过70%的植物;大球虫、长姜黄、圆形莎草和霸王typpha具有50-70%的溶栓活性;其余的植物有11% -49%的溶栓活性。这43种植物还包括香料和调味品，如姜黄、黑胡椒、印度贝叶、香菜和姜，这证实了以食为药的传统说法。此外，这些可食用植物还具有多种植物成分和有益健康的药理活性。如果将这些植物纳入日常饮食中，就有可能预防或延缓心血管疾病的发生。然而，需要详细的研究来评估食用这些植物的民族社区的心血管疾病模式，并需要系统的临床试验来研究这些植物的溶栓功效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biomedical and Pharmacology Journal Pharmacology, Toxicology and Pharmaceutics-Pharmacology

CiteScore

1.20

自引率

0.00%

发文量

189

期刊介绍： Biomedical and Pharmacology Journal (BPJ) is an International Peer Reviewed Research Journal in English language whose frequency is quarterly. The journal seeks to promote research, exchange of scientific information, consideration of regulatory mechanisms that affect drug development and utilization, and medical education. BPJ take much care in making your article published without much delay with your kind cooperation and support. Research papers, review articles, short communications, news are welcomed provided they demonstrate new findings of relevance to the field as a whole. All articles will be peer-reviewed and will find a place in Biomedical and Pharmacology Journal based on the merit and innovativeness of the research work. BPJ hopes that Researchers, Research scholars, Academician, Industrialists etc. would make use of this journal for the development of science and technology. Topics of interest include, but are not limited to: Biochemistry Genetics Microbiology and virology Molecular, cellular and cancer biology Neurosciences Pharmacology Drug Discovery Cardiovascular Pharmacology Neuropharmacology Molecular & Cellular Mechanisms Immunology & Inflammation Pharmacy.