A Susceptible Vaccinated Exposed Infected Hospitalized and Removed/Recovered (SVEIHR) Model Framework for COVID-19

None Oyamakin S. O., None Popoola J. I.
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Abstract

In reaction to the severe socio-economic effects and upheavals that the Covid-19 sickness had on the world within the first few weeks of its introduction, everyone involved had to act quickly to look for possible solutions for preventing the ensuing epidemics. A prompt response is more critical given Nigeria's subpar social, economic, and healthcare infrastructure. Investigated was the efficacy of various pharmacological, non-pharmaceutical, or a combination of both therapies in flattening the Covid-19 incidence curve. In order to investigate the impact of these interventions, a deterministic SVEIHR model was created and applied. The Nigerian Center for Disease Control (NCDC) portal's Covid-19 data were used to parametrize the model. For simulations using a system dynamic simulation, estimated parameters were employed. The fundamental reproduction number, R0, was used to evaluate the success of our suggested intervention in effectively managing COVID-19 transmission. The simulation results demonstrated that the use of only non-pharmaceutical interventions, such as the use of face masks, a light lockdown, and hand washing at baseline or high levels, is insufficient, with the R0 varying from vaccination at the vaccination rate of 0.5% with non-pharmaceutical interventions at any level of compliance, and a combination of vaccination at 0.05% and high hygiene level were effective in flattening the Covid-19 disease incidence curve in Nigeria, returning a R0 less than 1. Furthermore, maintaining a high level of cleanliness, which includes hand washing and the use of a face mask, would be sufficient to stop the spread of Covid-19 disease and eventually flatten Covid-19 disease incidence curve in Nigeria, given a low turnout of 0.05% for vaccination and the easing of lockdown.
COVID-19易感疫苗暴露、感染、住院和移除/恢复(SVEIHR)模型框架
Covid-19疾病在出现的最初几周内对世界造成了严重的社会经济影响和动荡,为此,所有相关人员都必须迅速采取行动,寻找可能的解决方案,以预防随后的流行病。鉴于尼日利亚的社会、经济和医疗基础设施落后,迅速作出反应更为关键。研究了各种药物治疗、非药物治疗或两种治疗联合使用对平坦Covid-19发病率曲线的疗效。为了研究这些干预措施的影响,我们创建并应用了一个确定性的SVEIHR模型。尼日利亚疾病控制中心(NCDC)门户网站的Covid-19数据用于参数化模型。对于采用系统动态仿真的仿真,采用估计参数。基本繁殖数R0用于评估我们建议的干预措施在有效管理COVID-19传播方面的成功程度。模拟结果表明,仅使用非药物干预措施(如使用口罩、轻度封锁和基线或高水平洗手)是不够的,R0不同于疫苗接种率为0.5%的疫苗接种率与任何依从性水平的非药物干预措施,以及0.05%的疫苗接种率和高卫生水平的疫苗接种率相结合,可有效地使尼日利亚的Covid-19发病率曲线变平。返回小于1的R0。此外,鉴于疫苗接种率仅为0.05%,且封锁措施有所放松,保持高水平的清洁,包括洗手和使用口罩,将足以阻止Covid-19疾病的传播,并最终使尼日利亚的Covid-19疾病发病率曲线趋于平缓。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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