EPIDEMIOLOGY AND PHARMACOTHERAPY OF ROTAVIRUS AND IMPACT OF VACCINATION TO PREVENTION ITS MORTALITY

Abstract

Rotavirus is a type of virus that primarily affects infants and young children, causing gastroenteritis, which is inflammation of the stomach and intestines. It is one of the leading reasons for server diarrhea worldwide,especially in developing lands. The virus is highly contagious and can spread through the fecal-oral route, primarily through contaminated food, water, and surfaces. The introduction of the rotavirus vaccines has had a significant impact on reducing the burden of rotavirus-related illnesses. Many countries have incorporated rotavirus vaccination into their national immunization programs. The vaccines havesignificantly reduced rotavirus-related hospitalizations, deaths, and overall disease burden in countries where vaccination coverage is high. Here, we will discuss the recent developments in epidemiology, diagnosis, and treatments of rotavirus-induced gastroenteritis. Moreover, suggestions to prevent incidences of infection have been elegantly discussed