Experience in the Morphological Study of Dorsolumbar Spine Deformities in Women over 50 Years

Ovidiu-Ioan Șușu, Rareș Vodă, Tamás Csaba Sipos, Zsuzsanna Pap
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Abstract

Abstract Introduction Osteoporosis is characterized by a reduction in bone mineral density. Among the factors that can contribute to the onset of osteoporosis we can enumerate alcohol consumption, smoking, glucocorticoid therapy, or the presence of diabetes mellitus. The incidence of osteoporosis increases with age. Materials and Methods A total of 183 women over the age of 50, with a mean age of 67.9 ± 7.74 years, were studied to visualize spinal column alterations. From this cohort, 103 patients underwent bone mineral density testing using dual-energy X-ray absorptiometry (DXA) and dorsolumbar radiography, while 80 patients did not undergo DXA testing. Assessment of the degree of vertebral involvement was performed using the Genant semiquantitative method. Results The highest percentage of vertebral fractures was observed in patients aged >70 years (100%). Within the studied cohort, 28% of patients displayed multiple vertebral fractures associated with age (p = 0.01). The most common site for vertebral involvement was the dorsolumbar region (D11–L2) across all age groups (p = 0.35). No statistically significant correlation (p = 0.22) was identified between DXA values and the presence of vertebral fractures, despite a trend of increased incidence of fractures as the T-score decreased. Conclusion Within the cohort, vertebral fractures were identified both in women with normal values of bone mineral density and in those with osteoporosis. Furthermore, the severity of these vertebral fractures did not correlate with bone mineral density values, highlighting the necessity of using both osteodensitometry and spinal radio-graphs for diagnosis.
50岁以上妇女腰背脊柱畸形的形态学研究体会
骨质疏松症的特点是骨密度降低。在导致骨质疏松的因素中,我们可以列举饮酒、吸烟、糖皮质激素治疗或糖尿病的存在。骨质疏松症的发病率随着年龄的增长而增加。材料与方法对183例50岁以上女性(平均年龄67.9±7.74岁)脊柱改变进行可视化研究。在该队列中,103例患者使用双能x线吸收仪(DXA)和腰背x线摄影进行了骨密度检测,而80例患者未进行DXA检测。采用Genant半定量方法评估椎体受累程度。结果70岁患者椎体骨折发生率最高(100%)。在研究队列中,28%的患者表现出与年龄相关的多发椎体骨折(p = 0.01)。在所有年龄组中,最常见的椎体受累部位是腰背区(D11-L2) (p = 0.35)。尽管随着t评分的降低,骨折的发生率有增加的趋势,但DXA值与椎体骨折的存在之间没有统计学意义的相关性(p = 0.22)。结论:在该队列中,骨密度正常的女性和骨质疏松症患者均可发现椎体骨折。此外,这些椎体骨折的严重程度与骨密度值无关,强调了使用骨密度测量和脊柱x线片进行诊断的必要性。
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